Quantitative Versus Qualitative Fecal Immunochemical Tests (FIT) to Prioritize Urgency of Colonoscopy Referral
Evaluating the Effectiveness of Screening Strategies Using Quantitative Versus Qualitative Fecal Immunochemical Test (FIT) to Prioritize Urgency of Colonoscopy Referral - a Randomized Controlled Trial Protocol
研究概览
地位
条件
详细说明
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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-
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Kuala Lumpur、马来西亚、59100
- University of Malaya Medical Centre
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Adults aged 50 years and above
Exclusion Criteria:
- Lower gastrointestinal tract symptoms such as diarrhoea, constipation, per rectal bleeding
- Personal history of colorectal tumour or cancer
- Family history of familial adenomatous polyposis or hereditary non-polyposis colorectal cancer
学习计划
研究是如何设计的?
设计细节
- 主要用途:放映
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:单身的
武器和干预
参与者组/臂 |
干预/治疗 |
---|---|
其他:Qualitative fecal immunochemical test
Stool samples will be tested with the qualitative fecal immunochemical test (qFIT), and will be stratified for colonoscopy as follows: >200 ng/dL - colonoscopy with one month 100-200 ng/dL - colonoscopy as per waiting list <100 ng/dL - no colonoscopy Cost analysis, anxiety scores and patient satisfaction scores will be calculated for all patients. |
This test measures the amount of blood within the submitted stool specimen
Patients with positive tests will be subjected to colonoscopy to determine presence or absence of advanced colorectal neoplasms.
Data on direct and indirect costs to patient and institution will be collected at each patient visit related to screening.
Hospital Anxiety and Depression Scale (HADS) questionnaire
A 5-point patient satisfaction score will be documented at each patient visit related to screening.
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其他:Quantitative fecal immunochemical test
Stool samples will be tested with the quantitative fecal immunochemical test (FIT), and will be scheduled for colonoscopy as follows: Positive - colonoscopy as per waiting list Negative - no colonoscopy Cost analysis, anxiety scores and patient satisfaction scores will be calculated for all patients. |
Patients with positive tests will be subjected to colonoscopy to determine presence or absence of advanced colorectal neoplasms.
Data on direct and indirect costs to patient and institution will be collected at each patient visit related to screening.
Hospital Anxiety and Depression Scale (HADS) questionnaire
A 5-point patient satisfaction score will be documented at each patient visit related to screening.
This test detects presence or absence of blood within a submitted stool specimen.
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Time to diagnosis of advanced colorectal neoplasms
大体时间:40-90 days from the time of enrolment
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Measured as number of days from the time of enrolment until histological diagnosis of a colorectal neoplasm
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40-90 days from the time of enrolment
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Analysis of screening costs
大体时间:Up to 90 days following enrolment
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Total costs incurred as a result of the screening process
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Up to 90 days following enrolment
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Patient anxiety levels
大体时间:Up to 90 days after enrolment
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As measured by the Hospital Anxiety and Depression Scale (HADS)
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Up to 90 days after enrolment
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合作者和调查者
调查人员
- 首席研究员:April C Roslani, MBBCh、University of Malaya Medical Centre
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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