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Effects of Cognitive Training on Speech Perception

2021年1月26日 更新者:Aaron Newman

Effects of Cognitive Training on Age-Related Hearing Loss and Speech Perception

In this study, the investigators are testing whether cognitive training can lead to improvements in speech perception for individuals with hearing loss. Individuals will complete 20 hours of cognitive training that is designed to improve cognitive abilities such as short term memory and attention. The investigators predict that cognitive training that improves the cognitive abilities affected by hearing loss will improve speech perception.

研究概览

研究类型

介入性

注册 (实际的)

42

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • Nova Scotia
      • Halifax、Nova Scotia、加拿大、B3H 4R2
        • NeuroCognitive Imaging Lab, Dalhousie University

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

50年 及以上 (成人、年长者)

接受健康志愿者

有资格学习的性别

全部

描述

Inclusion Criteria:

  • Able to come to Dalhousie University, Halifax, Nova Scotia, Canada for study visits
  • Adults (50 years or older) with mild to moderate hearing loss
  • Access to an internet-connected device that is able to use Flash media, basic computer skills
  • Medically stable participants
  • Not currently taking medication that may affect brain function (e.g., anti-anxiety medication)
  • Normal or corrected-to-normal vision

Exclusion Criteria:

  • Participants with neurological conditions such as epilepsy or concussions will be excluded for safety reasons
  • Participants who are not native English speakers (materials used in the study are only in English)
  • Participants who are unable to provide consent
  • Participants with impaired cognition (assessed with the Montreal Cognitive Assessment)
  • Participants with high accuracy on the Speech Perception in Noise task at the second study visit (to eliminate participants who may be performing at ceiling level)

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:单身的

武器和干预

参与者组/臂
干预/治疗
有源比较器:Control, cognitive training
Participants in the control arm will receive cognitive training for cognitive abilities not affected by age-related hearing loss.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

实验性的:Experimental, cognitive training
Participants in the experimental arm will receive cognitive training for cognitive abilities affected by age-related hearing loss.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

有源比较器:Active Control, crossword training
Participants in this group will undergo crossword puzzle training. The purpose of this group is control for any effects that may be due to engaging in cognitive training.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Speech Perception in Noise Test - Improvement in speech perception accuracy from baseline to post-training for high and low predictability sentences
大体时间:Baseline, Weeks 2, 10, and 18
Sentences of high predictability and low predictability are played with multi-user talker babble. Participants must repeat the last word of each sentence as they heard it. The primary outcome measure will be the accuracy for repeating the sentence.
Baseline, Weeks 2, 10, and 18

次要结果测量

结果测量
措施说明
大体时间
Working Memory Cognitive Training - Improvements in working memory abilities from baseline
大体时间:Weeks 2, 10, and 18

Individuals are asked to participate in 20 hours of cognitive training that will focus on either improving abilities affected by hearing loss (i.e., verbal working memory), or abilities not affected by hearing loss (i.e., spatial working memory).

Performance on the working memory task, Operation Span Task (OSPAN), will be assessed using the total score which is calculated as a sum based on the number of correct answers (letters accurately sequentially recalled) within a block for the duration of the task. Higher scores indicate better working memory capacity. Performance on the working memory cognitive training games will be assessed using the participant's accuracy, reaction time, and final score on the game.

Improvements in working memory will be assessed by comparing participant performance on working memory tasks (OSPAN; cognitive training memory games) before receiving cognitive training, immediately after receiving cognitive training, and eight weeks post-training.

Weeks 2, 10, and 18
Brain Performance Test
大体时间:Weeks 2 and 10
The Brain Performance Test (BPT) is an assessment tool available online through the training program website. Participants will be assessed at home on their initial performance for a variety of cognitive abilities including stop-signal tasks, grammatical reasoning, and memory spans. After completing the eight weeks of cognitive training, participants will again be assessed at home with the BPT to determine whether there are any improvements in cognitive abilities.
Weeks 2 and 10
Attention Cognitive Training - Improvements in attention abilities from baseline
大体时间:Weeks 2, 10, and 18

Individuals are asked to participate in 20 hours of cognitive training. Cognitive training will focus on either improving abilities affected by hearing loss (i.e., attention), or abilities not affected by hearing loss (i.e., spatial working memory).

Performance on the attention task, Flanker-Simon, will be assessed based on participant's accuracy and reaction time for the Flanker task, and the Simon task.

Performance on the attention cognitive training games will be assessed using the participant's accuracy, reaction time, and final score on the game.

Improvements in attention will be assessed by comparing the performance of participants on attention tasks (Flanker-Simon; cognitive training attention games) before receiving cognitive training, immediately after receiving cognitive training, and eight weeks post-training.

Weeks 2, 10, and 18

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

调查人员

  • 首席研究员:Aaron J Newman, PhD、Dalhousie University, Canada

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2016年9月1日

初级完成 (实际的)

2020年9月1日

研究完成 (实际的)

2020年9月1日

研究注册日期

首次提交

2014年11月3日

首先提交符合 QC 标准的

2014年11月17日

首次发布 (估计)

2014年11月19日

研究记录更新

最后更新发布 (实际的)

2021年1月27日

上次提交的符合 QC 标准的更新

2021年1月26日

最后验证

2021年1月1日

更多信息

与本研究相关的术语

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

Cognitive training的临床试验

3
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