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Effects of Cognitive Training on Speech Perception

26 de enero de 2021 actualizado por: Aaron Newman

Effects of Cognitive Training on Age-Related Hearing Loss and Speech Perception

In this study, the investigators are testing whether cognitive training can lead to improvements in speech perception for individuals with hearing loss. Individuals will complete 20 hours of cognitive training that is designed to improve cognitive abilities such as short term memory and attention. The investigators predict that cognitive training that improves the cognitive abilities affected by hearing loss will improve speech perception.

Descripción general del estudio

Estado

Terminado

Intervención / Tratamiento

Tipo de estudio

Intervencionista

Inscripción (Actual)

42

Fase

  • No aplica

Contactos y Ubicaciones

Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.

Ubicaciones de estudio

    • Nova Scotia
      • Halifax, Nova Scotia, Canadá, B3H 4R2
        • NeuroCognitive Imaging Lab, Dalhousie University

Criterios de participación

Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.

Criterio de elegibilidad

Edades elegibles para estudiar

50 años y mayores (Adulto, Adulto Mayor)

Acepta Voluntarios Saludables

No

Géneros elegibles para el estudio

Todos

Descripción

Inclusion Criteria:

  • Able to come to Dalhousie University, Halifax, Nova Scotia, Canada for study visits
  • Adults (50 years or older) with mild to moderate hearing loss
  • Access to an internet-connected device that is able to use Flash media, basic computer skills
  • Medically stable participants
  • Not currently taking medication that may affect brain function (e.g., anti-anxiety medication)
  • Normal or corrected-to-normal vision

Exclusion Criteria:

  • Participants with neurological conditions such as epilepsy or concussions will be excluded for safety reasons
  • Participants who are not native English speakers (materials used in the study are only in English)
  • Participants who are unable to provide consent
  • Participants with impaired cognition (assessed with the Montreal Cognitive Assessment)
  • Participants with high accuracy on the Speech Perception in Noise task at the second study visit (to eliminate participants who may be performing at ceiling level)

Plan de estudios

Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.

¿Cómo está diseñado el estudio?

Detalles de diseño

  • Propósito principal: Tratamiento
  • Asignación: Aleatorizado
  • Modelo Intervencionista: Asignación paralela
  • Enmascaramiento: Único

Armas e Intervenciones

Grupo de participantes/brazo
Intervención / Tratamiento
Comparador activo: Control, cognitive training
Participants in the control arm will receive cognitive training for cognitive abilities not affected by age-related hearing loss.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

Experimental: Experimental, cognitive training
Participants in the experimental arm will receive cognitive training for cognitive abilities affected by age-related hearing loss.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

Comparador activo: Active Control, crossword training
Participants in this group will undergo crossword puzzle training. The purpose of this group is control for any effects that may be due to engaging in cognitive training.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

¿Qué mide el estudio?

Medidas de resultado primarias

Medida de resultado
Medida Descripción
Periodo de tiempo
Speech Perception in Noise Test - Improvement in speech perception accuracy from baseline to post-training for high and low predictability sentences
Periodo de tiempo: Baseline, Weeks 2, 10, and 18
Sentences of high predictability and low predictability are played with multi-user talker babble. Participants must repeat the last word of each sentence as they heard it. The primary outcome measure will be the accuracy for repeating the sentence.
Baseline, Weeks 2, 10, and 18

Medidas de resultado secundarias

Medida de resultado
Medida Descripción
Periodo de tiempo
Working Memory Cognitive Training - Improvements in working memory abilities from baseline
Periodo de tiempo: Weeks 2, 10, and 18

Individuals are asked to participate in 20 hours of cognitive training that will focus on either improving abilities affected by hearing loss (i.e., verbal working memory), or abilities not affected by hearing loss (i.e., spatial working memory).

Performance on the working memory task, Operation Span Task (OSPAN), will be assessed using the total score which is calculated as a sum based on the number of correct answers (letters accurately sequentially recalled) within a block for the duration of the task. Higher scores indicate better working memory capacity. Performance on the working memory cognitive training games will be assessed using the participant's accuracy, reaction time, and final score on the game.

Improvements in working memory will be assessed by comparing participant performance on working memory tasks (OSPAN; cognitive training memory games) before receiving cognitive training, immediately after receiving cognitive training, and eight weeks post-training.

Weeks 2, 10, and 18
Brain Performance Test
Periodo de tiempo: Weeks 2 and 10
The Brain Performance Test (BPT) is an assessment tool available online through the training program website. Participants will be assessed at home on their initial performance for a variety of cognitive abilities including stop-signal tasks, grammatical reasoning, and memory spans. After completing the eight weeks of cognitive training, participants will again be assessed at home with the BPT to determine whether there are any improvements in cognitive abilities.
Weeks 2 and 10
Attention Cognitive Training - Improvements in attention abilities from baseline
Periodo de tiempo: Weeks 2, 10, and 18

Individuals are asked to participate in 20 hours of cognitive training. Cognitive training will focus on either improving abilities affected by hearing loss (i.e., attention), or abilities not affected by hearing loss (i.e., spatial working memory).

Performance on the attention task, Flanker-Simon, will be assessed based on participant's accuracy and reaction time for the Flanker task, and the Simon task.

Performance on the attention cognitive training games will be assessed using the participant's accuracy, reaction time, and final score on the game.

Improvements in attention will be assessed by comparing the performance of participants on attention tasks (Flanker-Simon; cognitive training attention games) before receiving cognitive training, immediately after receiving cognitive training, and eight weeks post-training.

Weeks 2, 10, and 18

Colaboradores e Investigadores

Aquí es donde encontrará personas y organizaciones involucradas en este estudio.

Patrocinador

Investigadores

  • Investigador principal: Aaron J Newman, PhD, Dalhousie University, Canada

Publicaciones y enlaces útiles

La persona responsable de ingresar información sobre el estudio proporciona voluntariamente estas publicaciones. Estos pueden ser sobre cualquier cosa relacionada con el estudio.

Fechas de registro del estudio

Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados ​​por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.

Fechas importantes del estudio

Inicio del estudio

1 de septiembre de 2016

Finalización primaria (Actual)

1 de septiembre de 2020

Finalización del estudio (Actual)

1 de septiembre de 2020

Fechas de registro del estudio

Enviado por primera vez

3 de noviembre de 2014

Primero enviado que cumplió con los criterios de control de calidad

17 de noviembre de 2014

Publicado por primera vez (Estimar)

19 de noviembre de 2014

Actualizaciones de registros de estudio

Última actualización publicada (Actual)

27 de enero de 2021

Última actualización enviada que cumplió con los criterios de control de calidad

26 de enero de 2021

Última verificación

1 de enero de 2021

Más información

Términos relacionados con este estudio

Plan de datos de participantes individuales (IPD)

¿Planea compartir datos de participantes individuales (IPD)?

NO

Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .

Ensayos clínicos sobre Cognitive training

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