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Effects of Cognitive Training on Speech Perception

26 de janeiro de 2021 atualizado por: Aaron Newman

Effects of Cognitive Training on Age-Related Hearing Loss and Speech Perception

In this study, the investigators are testing whether cognitive training can lead to improvements in speech perception for individuals with hearing loss. Individuals will complete 20 hours of cognitive training that is designed to improve cognitive abilities such as short term memory and attention. The investigators predict that cognitive training that improves the cognitive abilities affected by hearing loss will improve speech perception.

Visão geral do estudo

Status

Rescindido

Intervenção / Tratamento

Tipo de estudo

Intervencional

Inscrição (Real)

42

Estágio

  • Não aplicável

Contactos e Locais

Esta seção fornece os detalhes de contato para aqueles que conduzem o estudo e informações sobre onde este estudo está sendo realizado.

Locais de estudo

    • Nova Scotia
      • Halifax, Nova Scotia, Canadá, B3H 4R2
        • NeuroCognitive Imaging Lab, Dalhousie University

Critérios de participação

Os pesquisadores procuram pessoas que se encaixem em uma determinada descrição, chamada de critérios de elegibilidade. Alguns exemplos desses critérios são a condição geral de saúde de uma pessoa ou tratamentos anteriores.

Critérios de elegibilidade

Idades elegíveis para estudo

50 anos e mais velhos (Adulto, Adulto mais velho)

Aceita Voluntários Saudáveis

Não

Gêneros Elegíveis para o Estudo

Tudo

Descrição

Inclusion Criteria:

  • Able to come to Dalhousie University, Halifax, Nova Scotia, Canada for study visits
  • Adults (50 years or older) with mild to moderate hearing loss
  • Access to an internet-connected device that is able to use Flash media, basic computer skills
  • Medically stable participants
  • Not currently taking medication that may affect brain function (e.g., anti-anxiety medication)
  • Normal or corrected-to-normal vision

Exclusion Criteria:

  • Participants with neurological conditions such as epilepsy or concussions will be excluded for safety reasons
  • Participants who are not native English speakers (materials used in the study are only in English)
  • Participants who are unable to provide consent
  • Participants with impaired cognition (assessed with the Montreal Cognitive Assessment)
  • Participants with high accuracy on the Speech Perception in Noise task at the second study visit (to eliminate participants who may be performing at ceiling level)

Plano de estudo

Esta seção fornece detalhes do plano de estudo, incluindo como o estudo é projetado e o que o estudo está medindo.

Como o estudo é projetado?

Detalhes do projeto

  • Finalidade Principal: Tratamento
  • Alocação: Randomizado
  • Modelo Intervencional: Atribuição Paralela
  • Mascaramento: Solteiro

Armas e Intervenções

Grupo de Participantes / Braço
Intervenção / Tratamento
Comparador Ativo: Control, cognitive training
Participants in the control arm will receive cognitive training for cognitive abilities not affected by age-related hearing loss.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

Experimental: Experimental, cognitive training
Participants in the experimental arm will receive cognitive training for cognitive abilities affected by age-related hearing loss.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

Comparador Ativo: Active Control, crossword training
Participants in this group will undergo crossword puzzle training. The purpose of this group is control for any effects that may be due to engaging in cognitive training.

Participants will engage in eight weeks of training that focuses on improving various cognitive abilities. For example, short term memory.

Cognitive training will take place 30 minutes per day, five days per week, for eight weeks. Training will be done in the participant's own home using web-based software. Participants will be randomly assigned to either the active control group, the control cognitive training group, or the experimental cognitive training group following the second study visit.

After eight weeks, participants will no longer partake in training.

O que o estudo está medindo?

Medidas de resultados primários

Medida de resultado
Descrição da medida
Prazo
Speech Perception in Noise Test - Improvement in speech perception accuracy from baseline to post-training for high and low predictability sentences
Prazo: Baseline, Weeks 2, 10, and 18
Sentences of high predictability and low predictability are played with multi-user talker babble. Participants must repeat the last word of each sentence as they heard it. The primary outcome measure will be the accuracy for repeating the sentence.
Baseline, Weeks 2, 10, and 18

Medidas de resultados secundários

Medida de resultado
Descrição da medida
Prazo
Working Memory Cognitive Training - Improvements in working memory abilities from baseline
Prazo: Weeks 2, 10, and 18

Individuals are asked to participate in 20 hours of cognitive training that will focus on either improving abilities affected by hearing loss (i.e., verbal working memory), or abilities not affected by hearing loss (i.e., spatial working memory).

Performance on the working memory task, Operation Span Task (OSPAN), will be assessed using the total score which is calculated as a sum based on the number of correct answers (letters accurately sequentially recalled) within a block for the duration of the task. Higher scores indicate better working memory capacity. Performance on the working memory cognitive training games will be assessed using the participant's accuracy, reaction time, and final score on the game.

Improvements in working memory will be assessed by comparing participant performance on working memory tasks (OSPAN; cognitive training memory games) before receiving cognitive training, immediately after receiving cognitive training, and eight weeks post-training.

Weeks 2, 10, and 18
Brain Performance Test
Prazo: Weeks 2 and 10
The Brain Performance Test (BPT) is an assessment tool available online through the training program website. Participants will be assessed at home on their initial performance for a variety of cognitive abilities including stop-signal tasks, grammatical reasoning, and memory spans. After completing the eight weeks of cognitive training, participants will again be assessed at home with the BPT to determine whether there are any improvements in cognitive abilities.
Weeks 2 and 10
Attention Cognitive Training - Improvements in attention abilities from baseline
Prazo: Weeks 2, 10, and 18

Individuals are asked to participate in 20 hours of cognitive training. Cognitive training will focus on either improving abilities affected by hearing loss (i.e., attention), or abilities not affected by hearing loss (i.e., spatial working memory).

Performance on the attention task, Flanker-Simon, will be assessed based on participant's accuracy and reaction time for the Flanker task, and the Simon task.

Performance on the attention cognitive training games will be assessed using the participant's accuracy, reaction time, and final score on the game.

Improvements in attention will be assessed by comparing the performance of participants on attention tasks (Flanker-Simon; cognitive training attention games) before receiving cognitive training, immediately after receiving cognitive training, and eight weeks post-training.

Weeks 2, 10, and 18

Colaboradores e Investigadores

É aqui que você encontrará pessoas e organizações envolvidas com este estudo.

Patrocinador

Investigadores

  • Investigador principal: Aaron J Newman, PhD, Dalhousie University, Canada

Publicações e links úteis

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Datas de registro do estudo

Essas datas acompanham o progresso do registro do estudo e os envios de resumo dos resultados para ClinicalTrials.gov. Os registros do estudo e os resultados relatados são revisados ​​pela National Library of Medicine (NLM) para garantir que atendam aos padrões específicos de controle de qualidade antes de serem publicados no site público.

Datas Principais do Estudo

Início do estudo

1 de setembro de 2016

Conclusão Primária (Real)

1 de setembro de 2020

Conclusão do estudo (Real)

1 de setembro de 2020

Datas de inscrição no estudo

Enviado pela primeira vez

3 de novembro de 2014

Enviado pela primeira vez que atendeu aos critérios de CQ

17 de novembro de 2014

Primeira postagem (Estimativa)

19 de novembro de 2014

Atualizações de registro de estudo

Última Atualização Postada (Real)

27 de janeiro de 2021

Última atualização enviada que atendeu aos critérios de controle de qualidade

26 de janeiro de 2021

Última verificação

1 de janeiro de 2021

Mais Informações

Termos relacionados a este estudo

Plano para dados de participantes individuais (IPD)

Planeja compartilhar dados de participantes individuais (IPD)?

NÃO

Essas informações foram obtidas diretamente do site clinicaltrials.gov sem nenhuma alteração. Se você tiver alguma solicitação para alterar, remover ou atualizar os detalhes do seu estudo, entre em contato com register@clinicaltrials.gov. Assim que uma alteração for implementada em clinicaltrials.gov, ela também será atualizada automaticamente em nosso site .

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