Water Intake and Glycemic Response : Preliminary Study
2015年12月4日 更新者：Nutrifood Research Center, Jakarta, Indonesia
Glycemic index concept is widely used to determine impact of a food to blood glucose.
Several studies showed that water content and intake after meal may influence glycemic response of the meal and thus have an effect on the result of GI measurement.
Currently these studies found conflicting results.
Therefore, this study aims to determine whether water intake, specifically after meal, may influence the glycemic response and glycemic index value of the meal.
研究概览
地位
未知
条件
详细说明
Glycemic index methods are performed according to Food and Agricultural Organization/WHO recommendations.
研究类型
介入性
注册 (预期的)
10
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
DKI Jakarta
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Jakarta、DKI Jakarta、印度尼西亚、13920
- 招聘中
- PT Nutrifood Indonesia
-
接触：
- Astri Kurniati, MAppSc
- 邮箱：astri@nutrifood.co.id
-
-
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
20年 至 40年 (成人)
接受健康志愿者
不
有资格学习的性别
全部
描述
Inclusion Criteria:
- Age between 20-40 years
- fasting blood glucose 70-99 mg/dL
- Indonesians
Exclusion Criteria:
- having diabetes
- smoking
- if women, pregnant or lactating
- being allergic to food used in this study
- having gastrointestinal disturbance
- in regular medication
- refusal to sign the consent form
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：基础科学
- 分配：随机化
- 介入模型：交叉作业
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Glucose Ref - Std
250 ml glucose solution with 50 gram available carbohydrate per serving, used as reference
|
First, fasting blood glucose was measured.
Then, subjects consumed the glucose sample in 5-10 minutes and blood sugar level were measured at 0', 15', 30', 45', 60', 90', and 120'
|
|
实验性的：Glucose Ref and 450 ml water
250 ml glucose solution with 50 gram available carbohydrate per serving.
Sample was consumed with additional water intake @150 ml at 45, 75, and 105 minutes after meal consumption
|
First, fasting blood glucose was measured.
Then, subjects consumed the glucose sample in 5-10 minutes.
Subjects given additional 150 ml water at 45, 75, and 105 minutes and blood sugar level were measured at 0', 15', 30', 45', 60', 90', and 120
|
|
实验性的：White Bread with 250 ml water
White bread with 50 gram available carbohydrate was consumed with 250 ml water immediately after meal consumption
|
First, fasting blood glucose was measured.
Then, subjects consumed the samples in 10-15 minutes and blood sugar level were measured at 0', 15', 30', 45', 60', 90', and 120'
|
|
实验性的：White Bread and 700 ml water
White bread with 50 gram available carbohydrate was consumed with 250 ml water immediately after meal consumption.
Moreover, subjects given additional water intake @150 ml at 45, 75, and 105 minutes after meal consumption
|
Sample consumed with 250 ml water immediately after meal consumption, and additional 150 ml water at 45, 75, and 105 minutes. First, fasting blood glucose was measured. Then, subjects consumed the samples in 10-15 minutes and blood sugar level were measured at 0', 15', 30', 45', 60', 90', and 120' |
|
实验性的：White Bread with 125 ml water (twice)
Sample consumed with 125 ml water immediately after meal consumption, and additional 125 ml water after 60 minutes
|
Sample consumed with 125 ml water immediately after meal consumption, and additional 125 ml water after 60 minutes First, fasting blood glucose was measured. Then, subjects consumed the samples in 10-15 minutes and blood sugar level were measured at 0', 15', 30', 45', 60', 90', and 120' |
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
2 h postprandial blood glucose level (Glycemic Response)
大体时间：fasting 0 min, 15 min, 30 min, 45 min, 60 min, 90 min, 120 min
|
fasting 0 min, 15 min, 30 min, 45 min, 60 min, 90 min, 120 min
|
|
|
Glycemic index value of meal (white bread)
大体时间：fasting 0 min, 15 min, 30 min, 45 min, 60 min, 90 min, 120 min
|
The glycemic index is a calculated from measurements of area under the glucose curve after the food is eaten, divided by the corresponding area after the control food is eaten.
The value is multiplied by 100 to represent a percentage of the reference food.
|
fasting 0 min, 15 min, 30 min, 45 min, 60 min, 90 min, 120 min
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Vanessa Yolanda, Ssi、Nutrifood Research Center
- 学习椅：Astri Kurniati, MAppSc、Nutrifood Research Center
- 首席研究员：Lina Antono, MSc、Nutrifood Research Center
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Carbohydrates in human nutrition. Report of a Joint FAO/WHO Expert Consultation. FAO Food Nutr Pap. 1998;66:1-140. No abstract available.
- Young KWH, Wolever TMS. Effect of volume and type of beverage consumed with a standard test meal on postprandial blood glucose responses. Nutrition Research 18(11): 1857-1863, 1998
- Torsdottir I, Andersson H. Effect on the postprandial glycaemic level of the addition of water to a meal ingested by healthy subjects and type 2 (non-insulin-dependent) diabetic patients. Diabetologia. 1989 Apr;32(4):231-5. doi: 10.1007/BF00285289.
- Gregersen S, Rasmussen O, Winther E, Hermansen K. Water volume and consumption time: influence on the glycemic and insulinemic responses in non-insulin-dependent diabetic subjects. Am J Clin Nutr. 1990 Sep;52(3):515-8. doi: 10.1093/ajcn/52.3.515.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始
2015年11月1日
初级完成 (预期的)
2015年12月1日
研究完成 (预期的)
2015年12月1日
研究注册日期
首次提交
2015年11月16日
首先提交符合 QC 标准的
2015年12月4日
首次发布 (估计)
2015年12月9日
研究记录更新
最后更新发布 (估计)
2015年12月9日
上次提交的符合 QC 标准的更新
2015年12月4日
最后验证
2015年12月1日
更多信息
与本研究相关的术语
关键字
其他研究编号
- Nutrifood
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
Glucose Ref - Std的临床试验
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National Development and Research Institutes, Inc.St. Luke's-Roosevelt Hospital Center; Daytop (adolescent treament program)未知
-
University of PennsylvaniaNational Institute of Mental Health (NIMH); University of California, Los Angeles; Columbia University 和其他合作者完全的
-
University of PennsylvaniaNational Institute of Mental Health (NIMH)完全的
-
Pacific Institute for Research and EvaluationNational Institute of Mental Health (NIMH)完全的