脓毒症治疗期间 MAPSE 的变化
急诊脓毒症患者二尖瓣环收缩平面偏移 (MAPSE) 的评估
Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the form of low blood pressure (shock) and heart failure. Ultrasound is frequently used in the emergency department to evaluate why a patient might have low blood pressure. Part of that evaluation may include obtaining ultrasound images and making measurements about how well or poorly the heart is pumping. The investigators will evaluate a certain measurement that relates to cardiac function, determine how it changes in patients before and after they are treated for septic shock. This will involve placing an ultrasound probe on the patient's chest, measuring the upward and downward movement of the mitral valve, the mitral annulus systolic plane excursion (MAPSE), and comparing the measurements before and after treatment is started. The investigators are attempting to determine if this measurement improves before and after treatment.
研究概览
研究类型
注册 (估计的)
联系人和位置
学习联系方式
- 姓名:Alexis Salerno, MD
- 电话号码:(667) 214-2208
- 邮箱:alexis.salerno@som.umaryland.edu
学习地点
-
-
Maryland
-
Baltimore、Maryland、美国、21201
- 招聘中
- University of Maryland Medical Center
-
接触:
- Alexis Salerno, MD
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
adult emergency department patients who present with sepsis
描述
Inclusion Criteria:
- Diagnosis of Sepsis or Septic Shock
Exclusion Criteria:
- Age equal to or less than 17
- patient in the emergency department
- Unable to perform POCUS exam due to medical necessity
- Patients without sepsis
- unable to obtain consent or have a legal representative consent
学习计划
研究是如何设计的?
设计细节
- 观测模型:COHORT
- 时间观点:PROSPECTIVE
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
|
Patients with Sepsis
These are patients who present to the emergency department with sepsis. They will have a MAPSE at the time of enrollment and then after initial treatment. |
Patients will have standard care of sepsis |
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Change in MAPSE measurement
大体时间:1 hour after treatment initiation
|
Does the MAPSE change after treatment of MAPSE |
1 hour after treatment initiation
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.