八段锦运动对改善久坐中青年健康的影响
一项多中心随机对照试验：评估八段锦对改善久坐中青年人群健康结局的疗效及机制研究
The goal of this clinical trial is to learn if a 12-week Baduanjin exercise program can improve health in sedentary young and middle-aged adults. The main questions it aims to answer are:
- Does the Baduanjin program improve participants' cardiorespiratory fitness (measured as peak oxygen uptake)?
- Does it improve their body composition, muscle strength, balance, and flexibility?
- Does it reduce their daily sitting time?
Researchers will compare the Baduanjin training group to a health education control group to see if Baduanjin is more effective in improving these health outcomes.
Participants will:
- Be randomly assigned to one of the two groups.
- If in the Baduanjin group, attend supervised group sessions and practice at home for 12 weeks.
- Complete a series of assessments at the beginning, middle, and end of the study, including fitness tests, body measurements, and questionnaires.
研究概览
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名：Jingyi Ren, M.D., Chief Physician
- 电话号码：18600195099
- 邮箱：renjingyi@cjfh.org.cn
学习地点
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Beijing Municipality
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Beijing、Beijing Municipality、中国、100029
- 招聘中
- China-Japan Friendship Hospital
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接触：
- Jingyi Ren, Doctor
- 电话号码：+86 17367938350
- 邮箱：1220193509@qq.com
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Adults aged 18 to 59 years
- Sedentary and physically inactive, defined as: (a) self-reported sitting time ≥ 8 hours per day, AND (b) not meeting the World Health Organization (WHO) recommended level of physical activity ( engaging in < 150 minutes of moderate-to-vigorous intensity physical activity per week, assessed by the International Physical Activity Questionnaire [IPAQ])
- In good general health as self-reported, and free from any known diseases
- Willing and able to provide written informed consent
Exclusion Criteria:
- Contraindications to cardiopulmonary exercise testing
- Currently participating in, or planning to participate within the next 3 months, in any other structured exercise or behavioral intervention program
- Pregnancy, lactation, or planning to become pregnant during the study period
- Inability to understand or comply with the study procedures
学习计划
研究是如何设计的？
设计细节
- 主要用途：预防
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Baduanjin Training Group
Participants in this group will receive a 12-week Baduanjin exercise program. The program consists of supervised group sessions combined with home-based practice, with a frequency of 5 sessions per week. Each session lasts 60 minutes, including warm-up, standardized Baduanjin practice, and cool-down. The Baduanjin exercises follow a standardized protocol. |
A 12-week, standardized Baduanjin exercise program. Participants will complete 5 sessions per week, each lasting 60 minutes (including warm-up, Baduanjin practice, and cool-down). The program includes both supervised group sessions and guided home practice. |
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其他：Health Education Control Group
Participants in this group will receive general health education, which includes recommendations on physical activity types and duration (e.g., following the WHO guidelines). However, they will not be enrolled in any structured, supervised exercise program. They will be instructed to maintain their usual lifestyle throughout the study period. |
Participants will receive general health education (including recommendations on physical activity types and duration), but will not be enrolled in any structured or supervised exercise program. They will be instructed to maintain their usual lifestyle. |
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Change in Peak Oxygen Uptake (VO₂peak) assessed by Cardiopulmonary Exercise Testing
大体时间：at baseline and Week 13.
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Measured by Cardiopulmonary Exercise Testing (CPET). |
at baseline and Week 13.
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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通过国际体力活动问卷（IPAQ）评估的久坐行为时间变化
大体时间：在基线和第13周时。
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在基线和第13周时。
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通过等速肌力测定评估的膝关节伸展平均功率变化
大体时间：在基线时、第8周和第13周。
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在基线时、第8周和第13周。
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通过等速肌力测试评估的膝关节伸展疲劳指数变化
大体时间：在基线期、第8周和第13周。
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在基线期、第8周和第13周。
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通过等速肌力测定评估的膝关节屈曲平均功率变化
大体时间：在基线、第8周和第13周
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在基线、第8周和第13周
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通过等速肌力测试评估的膝关节屈曲疲劳指数变化
大体时间：在基线、第8周和第13周
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在基线、第8周和第13周
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通过等速肌力测力评估的肩关节屈曲平均功率变化
大体时间：在基线、第8周和第13周
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在基线、第8周和第13周
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通过等速肌力测试评估的肩关节屈曲疲劳指数变化
大体时间：在基线、第8周和第13周
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在基线、第8周和第13周
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通过等速肌力测试评估的肩关节外展平均功率变化
大体时间：基线、第8周和第13周
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基线、第8周和第13周
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通过等速肌力测试评估的肩外展疲劳指数变化
大体时间：基线时、第8周和第13周
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基线时、第8周和第13周
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通过等速肌力测量评估的肘部伸展平均功率变化
大体时间：在基线时、第8周和第13周
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在基线时、第8周和第13周
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通过等速肌力测定评估的肘关节伸展疲劳指数变化
大体时间：在基线、第8周和第13周
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在基线、第8周和第13周
|
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通过等速肌力测试评估的肘关节屈曲平均功率变化
大体时间：在基线、第8周和第13周
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在基线、第8周和第13周
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通过等速肌力测力法评估的肘关节屈曲疲劳指数变化
大体时间：在基线、第8周和第13周
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在基线、第8周和第13周
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通过生物电阻抗分析评估的肌肉质量变化
大体时间：在基线和第13周。
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在基线和第13周。
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通过生物电阻抗分析法评估的体脂百分比变化
大体时间：在基线和第13周。
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在基线和第13周。
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通过生物电阻抗分析评估的无脂肪质量变化
大体时间：在基线和第13周。
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在基线和第13周。
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通过3D运动捕捉评估八段锦锻炼过程中质心高度的变化
大体时间：在基线和第13周
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在基线和第13周
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通过表面肌电图评估八段锦锻炼期间积分肌电图（iEMG）的变化
大体时间：基线时和第13周时
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基线时和第13周时
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通过表面肌电图评估八段锦锻炼期间均方根（RMS）振幅的变化
大体时间：在基线和第13周
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在基线和第13周
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完成的八段锦处方课程百分比
大体时间：直至研究完成，最长至第13周。
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直至研究完成，最长至第13周。
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Change in Sit-and-Reach Distance
大体时间：at baseline, Week 8, and Week 13.
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Assessed by the standard sit-and-reach test. |
at baseline, Week 8, and Week 13.
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Change in Active Range of Motion of the Shoulder, Hip, Knee, and Ankle joints assessed by Goniometry
大体时间：at baseline, Week 8, and Week 13.
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Measured using a goniometer |
at baseline, Week 8, and Week 13.
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Scores on the Exercise Benefits/Barriers Scale (EBBS)
大体时间：at baseline and Week 13
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The scale consists of two subscales: the Exercise Benefits Subscale (29 items) and the Exercise Barriers Subscale (14 items). The total score ranges from 43 to 172, with a higher score indicating a more positive perception towards exercise. |
at baseline and Week 13
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Change in Knee Extension Peak Torque assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13.
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Maximum torque generated during knee extension |
at baseline, Week 8, and Week 13.
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Change in Knee Extension Total Work assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13.
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Total work performed during repeated maximal knee extension contractions. |
at baseline, Week 8, and Week 13.
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Change in Knee Flexion Peak Torque assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
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Maximum torque generated during Knee Flexion measured at a preset angular velocity |
at baseline, Week 8, and Week 13
|
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Change in Knee Flexion Total Work assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
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Total work performed during repeated maximal Knee Flexion contractions |
at baseline, Week 8, and Week 13
|
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Change in Shoulder Flexion Peak Torque assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
|
Maximum torque generated during Shoulder Flexion, measured at a preset angular velocity. |
at baseline, Week 8, and Week 13
|
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Change in Shoulder Flexion Total Work assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
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Total work performed during repeated maximal Shoulder Flexion contractions |
at baseline, Week 8, and Week 13
|
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Change in Shoulder Abduction Peak Torque assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
|
Maximum torque generated during Shoulder Abduction , measured at a preset angular velocity |
at baseline, Week 8, and Week 13
|
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Change in Shoulder Abduction Total Work assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
|
Total work performed during repeated maximal Shoulder Abduction contractions |
at baseline, Week 8, and Week 13
|
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Change in Elbow Extension Peak Torque assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
|
Maximum torque generated during Elbow Extension, measured at a preset angular velocity |
at baseline, Week 8, and Week 13
|
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Change in Elbow Extension Total Work assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
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Total work performed during repeated maximal Elbow Extension contractions |
at baseline, Week 8, and Week 13
|
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Change in Elbow Flexion Peak Torque assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
|
Maximum torque generated during Elbow Flexion, measured at a preset angular velocity |
at baseline, Week 8, and Week 13
|
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Change in Elbow Flexion Total Work assessed by Isokinetic Dynamometry
大体时间：at baseline, Week 8, and Week 13
|
Total work performed during repeated maximal Elbow Flexion contractions |
at baseline, Week 8, and Week 13
|
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Change in Rhythmic Weight Shift (RWS) Score assessed by Computerized Dynamic Posturography
大体时间：at baseline, Week 8, and Week 13.
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Measured using a computerized dynamic posturography system. |
at baseline, Week 8, and Week 13.
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Change in Modified Clinical Test of Sensory Interaction on Balance (mCTSIB) Score assessed by Computerized Dynamic Posturography
大体时间：at baseline, Week 8, and Week 13.
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Measured using a computerized dynamic posturography system. |
at baseline, Week 8, and Week 13.
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Change in Sensory Organization Test (SOT) Composite Score assessed by Computerized Dynamic Posturography
大体时间：at baseline, Week 8, and Week 13.
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Measured using a computerized dynamic posturography system. |
at baseline, Week 8, and Week 13.
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Change in Motor Control Test (MCT) Latency assessed by Computerized Dynamic Posturography
大体时间：at baseline, Week 8, and Week 13.
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Measured using a computerized dynamic posturography system. |
at baseline, Week 8, and Week 13.
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Change in Limits of Stability (LOS) Score assessed by Computerized Dynamic Posturography
大体时间：at baseline, Week 8, and Week 13.
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Measured using a computerized dynamic posturography system. |
at baseline, Week 8, and Week 13.
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Change in Waist-to-Hip Ratio
大体时间：at baseline and Week 13.
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Ratio of waist circumference to hip circumference |
at baseline and Week 13.
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Change in Center of Mass Sway Amplitude during Baduanjin Exercise assessed by 3D Motion Capture
大体时间：at baseline and Week 13
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Magnitude of anteroposterior and mediolateral displacement of the body's center of mass during static postures of Baduanjin, analyzed using a markerless 3D motion capture system |
at baseline and Week 13
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Change in Joint Range of Motion during Baduanjin Exercise assessed by 3D Motion Capture
大体时间：at baseline and Week 13
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Angular displacement of primary joints during the performance of Baduanjin movements, analyzed using a markerless 3D motion capture system. |
at baseline and Week 13
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Change in Glycemic Control Biomarkers
大体时间：at baseline and Week 13.
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Fasting venous blood samples will be analyzed for indicators of glucose metabolism, such as glycated hemoglobin (HbA1c) and fasting insulin. |
at baseline and Week 13.
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Change in Lipid Profile
大体时间：at baseline and Week 13.
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Fasting venous blood samples will be analyzed for indicators of lipid metabolism, including total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). |
at baseline and Week 13.
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Change in Inflammatory and Neurotrophic Biomarkers
大体时间：at baseline and Week 13.
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Fasting venous blood samples will be analyzed for inflammatory markers (e.g., high-sensitivity C-reactive protein [hs-CRP], interleukin-6 [IL-6], tumor necrosis factor-alpha [TNF-α]) and brain-derived neurotrophic factor (BDNF). |
at baseline and Week 13.
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Baduanjin Movement Quality Score assessed by Blinded Expert Review (100-point scale)
大体时间：at Week 13
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Score assessed by blinded experts using a standardized 100-point scoring rubric. Scores range from 0 to 100, with a higher score indicating better movement quality. |
at Week 13
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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