- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00528736
Plasma B-Type Natriuretic Peptide Concentrations in Preterm Infants < 28 Weeks
Study Overview
Status
Detailed Description
From the study infants blood samples (0.1ml) were collected in K-EDTA microtubes within 24 to 48 hours of age through umbilical artery catheter aspiration or routine venous puncture. The samples were spun at 7000 rpm for 3 minutes. Platelet-free plasma was stored at -20°C until BNP analysis of all collected samples was carried out. The BNP assay was performed using a fully automated immunoassay system ADVIA method for the Centaur System (Bayer Diagnostic Division).
In preterm infants who were treated with indomethacin or surgical ligation we collected additional blood samples 2-4 hours before intervention and 24 hours after the completion of the ductus treatment.
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
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Berlin, Germany, 13353
- Department of Neonatology, Charite Virchow Hospital, Medical University Berlin
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Written parental informed consent
- Preterm infant < 28 weeks of gestation
- Admitted to our NICU within 48 hours after birth
Exclusion Criteria:
- No written parental informed consent,
- Congenital heart disease,
- Death
Study Plan
How is the study designed?
Design Details
Collaborators and Investigators
Investigators
- Study Director: Christoph Czernik, MD, Department of Neonatology, Charite Virchow Hospital, Medical University Berlin
Study record dates
Study Major Dates
Study Start
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- EA2/198/05
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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