Mitral Valve Area Assessment: Comparison With Transthoracic Echocardiography and Magnetic Resonance Imaging

April 7, 2008 updated by: Florence Nightingale Hospital, Istanbul

Quantification of Rheumatic Mitral Stenosis With Cardiac Magnetic Resonance Imaging and Comparison With Transthoracic Echocardiography

To compare mitral valve area in rheumatic mitral valve stenosis with cardiac magnetic resonance imaging and conventional transthoracic echocardiography.

Study Overview

Status

Unknown

Conditions

Detailed Description

Clinical assessment of severity of mitral stenosis depends on both the presence of symptoms and mitral valve area . Evaluation of mitral valve area with transthoracic echocardiography maintains rapid, accurate analysis of valve disease and serves as a practical gold standard for clinical evaluation. Cardiac magnetic resonance imaging (CMRI) is a recently used method that allows to evaluate cardiac structures and function noninvasively. Direct visualization of valve area with CMRI is also possible and it has been shown that the valve area assessed by CMRI planimetry correlates reliably with the invasive assessment. Velocity-encoded cardiac magnetic resonance imaging can be used to quantify mitral valve area. The objective of this study was to evaluate mitral valve area with CMRI and compare it with echocardiographic methods including 2D planimetry, Doppler continuation equation and Doppler pressure half-time

Study Type

Observational

Enrollment (Anticipated)

30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

  • Name: Özlem Yıldırımtürk, Professor
  • Phone Number: 4020 00902122244950
  • Email: ozlemyt@gmail.com

Study Locations

  • Turkey
      • Istanbul, Turkey, 34381
        • Recruiting
        • Florence Nightinngale Hospital
        • Contact:
        • Contact:
          • Özlem Yıldırımtürk, MD
          • Phone Number: 4020 00902122244950
          • Email: ozlemyt@gmail.com
      • Istanbul, Turkey, 34381
        • Recruiting
        • TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology
        • Contact:
        • Sub-Investigator:
          • Özlem Yıldırımtürk, MD
        • Principal Investigator:
          • Saide Aytekin, Professor
        • Sub-Investigator:
          • Aylin Tuğcu, MD
        • Sub-Investigator:
          • Yelda Tayyareci, MD
        • Sub-Investigator:
          • Onur Levent Ulusoy, MD
        • Sub-Investigator:
          • Cihan Duran, MD
        • Sub-Investigator:
          • Mustafa Şirvancı, MD

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

tertiary care clinic

Description

Inclusion Criteria:

  • rheumatic mitral valve stenosis

Exclusion Criteria:

  • Degenerative mitral valve disease
  • EF<50%
  • atrial fibrillation
  • inconclusive planimetric assessment
  • moderate or severe mitral regurgitation
  • moderate or severe aortic regurgitation
  • history of previous mitral valve commissurotomy or balloon valvotomy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
A
Mitral valve area above 1.5 cm2
B
Mitral valve area 1.5 cm2 and below 1.5 cm2

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Florence Nightingale Hospital, Istanbul

Investigators

  • Study Director: Saide Aytekin, Professor, T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

April 1, 2008

Primary Completion (Anticipated)

June 1, 2008

Study Completion (Anticipated)

June 1, 2008

Study Registration Dates

First Submitted

April 2, 2008

First Submitted That Met QC Criteria

April 7, 2008

First Posted (Estimate)

April 8, 2008

Study Record Updates

Last Update Posted (Estimate)

April 8, 2008

Last Update Submitted That Met QC Criteria

April 7, 2008

Last Verified

April 1, 2008

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • OY1975

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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