- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00960817
"Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up
August 17, 2009 updated by: Hillel Yaffe Medical Center
The investigators will investigate patients undergoing coronary angiography with normal coronary but slow blood flow that was normalized after adenosine injection into the coronary artery.
The investigators believe that they have small vessel coronary disease which is the initial presentation of coronary disease prior to anatomical narrowing.
To alleviate this phenomenon the investigators intend to examine the long-term clinical response of these patients to treatment with dipyridamole, a well-known medication with almost no side-effects that increases the level of adenosine in the tissue.
Study Overview
Status
Unknown
Conditions
Intervention / Treatment
Study Type
Interventional
Phase
- Early Phase 1
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Hadera, Israel, 38100
- Hillel Yaffe Medical Center
-
Principal Investigator:
- Aaron Frimerman, MD
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 80 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Patients undergoing coronary angiography and who have normal coronary artery with slow blood flow that normalized with adenosine injection into the coronary artery
Exclusion Criteria:
- Significant coronary disease
- Unstable patients
- Patients with known sensitivity to dipyridamole
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: 1. Routine treatment
Control group
|
|
Experimental: 2. Dipyridamole treatment
Group that receives Dipyridamole treatment
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Alleviation of chest pain
Time Frame: Two years
|
Two years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
August 17, 2009
First Submitted That Met QC Criteria
August 17, 2009
First Posted (Estimate)
August 18, 2009
Study Record Updates
Last Update Posted (Estimate)
August 18, 2009
Last Update Submitted That Met QC Criteria
August 17, 2009
Last Verified
August 1, 2009
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Physiological Effects of Drugs
- Molecular Mechanisms of Pharmacological Action
- Vasodilator Agents
- Peripheral Nervous System Agents
- Enzyme Inhibitors
- Analgesics
- Sensory System Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Antirheumatic Agents
- Fibrinolytic Agents
- Fibrin Modulating Agents
- Platelet Aggregation Inhibitors
- Cyclooxygenase Inhibitors
- Antipyretics
- Phosphodiesterase Inhibitors
- Aspirin
- Dipyridamole
Other Study ID Numbers
- HYMC 02/2009
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Coronary Angiography
-
Baylor Research InstituteUnknownCoronary Angioplasty | Coronary AngiographyUnited States
-
Ospedale Sandro Pertini, RomaRecruitingPercutaneous Coronary Intervention | Coronary AngiographyItaly
-
Fundación Pública Andaluza Progreso y SaludHospital Universitario Reina Sofia de CordobaCompletedCoronary AngiographySpain
-
Meir Medical CenterCompletedCoronary AngiographyIsrael
-
GCS Ramsay Santé pour l'Enseignement et la RechercheRecruitingCoronary AngiographyFrance
-
University of FloridaCompletedCoronary AngiographyUnited States
-
University of PatrasCompletedCoronary AngiographyGreece
-
Far Eastern Memorial HospitalCompletedCoronary Angiography | CTTaiwan
Clinical Trials on Statin, aspirin
-
Organon and CoMerck Sharp & Dohme LLCCompletedHypercholesterolemia | Coronary Heart Disease | Hyperlipidemia
-
Antalya Training and Research HospitalCompleted
-
National Taiwan University HospitalCompletedOut-Of-Hospital Cardiac ArrestTaiwan
-
Faculty of Medicine, Tarumanagara UniversityCengkareng General HospitalCompletedAcute Coronary Syndrome | Cardiogenic Shock | Recurrent Myocardial InfarctionIndonesia
-
Taipei Medical University WanFang HospitalTerminated
-
University of Sao Paulo General HospitalUnknownAneurysmal Subarachnoid HemorrhageBrazil
-
Radboud University Medical CenterErasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam...Completed
-
Translational Research Center for Medical Innovation...National Cerebral and Cardiovascular Center; Ministry of Health, Labour and... and other collaboratorsCompleted
-
National Taiwan University HospitalUnknown
-
Capital Medical UniversityRecruitingIntracerebral Hemorrhage | StatinsChina