- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01129999
Cognitive-Behavioral Therapy and Hypnotherapy for Smoking Cessation (CBT-HT)
February 3, 2014 updated by: Anil Batra, University Hospital Tuebingen
The Comparative Efficacy of Cognitive-Behavioral Therapy (CBT) and Hypnotherapy (HT) for Smoking Cessation.
Intensive cognitive-behaviour interventions (CBT) combined with pharmacotherapy for smoking cessation are well established and have been proved to be efficacious.
Nevertheless, they yield only long-term abstinence rates about 35%.
Considering the high interest of smokers in alternative medicine, the availability of a broad range of treatment methods, of which smokers choose an intervention according to their preferences, might contribute to improve treatment outcome.
While hypnotherapy (HT) is an already widely promoted alternative method for aiding cessation, considerable methodological shortcomings of studies on this topic limit the interpretability of the results.
In 2006, the German Academic Advisory Committee for Psychotherapy released new guidelines that included HT as an acceptable treatment for smoking cessation.
The committee conceded, however, that conclusions concerning its efficacy are restricted due to the heterogeneity of findings.
Hence, further well-designed studies are required to better test the efficacy of HT in comparison to accepted treatments.
This randomised, controlled trial aims to compare the efficacy of CBT and HT for smoking cessation.
Further, the influence of moderating variables will be investigated.
It is hypothesized that 1) participants receiving CBT will evince higher abstinence rates than those receiving HT, 2) levels of nicotine dependence, self-efficacy and motivation to change will moderate the intervention effects and 3) participants with high levels of suggestibility will evince higher abstinence rates in the HT-intervention compared to participants with low levels of suggestibility.
220 adult healthy smokers will be randomized to receive either CBT or HT.
Both programmes will be conducted in 6, weekly, 90-minute group sessions.
Participants will be followed up at 1, 3, 6, 9 und 12 month post-treatment.
Generalized estimating equation models will be conducted to analyse group differences on abstinence rates.
The models will include the above mentioned moderator variables.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
360
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Tuebingen, Germany, 72070
- University Hospital of Tuebingen Smoking Cessation Research Group
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- at least 18 years of age
- smoking at least 10 cigarettes per day
- smoking at least for the past two years
- fluency in German language
- willing and able to give written informed consent
Exclusion Criteria:
- women: planned or current pregnancy or breast-feeding
- participation in a smoking cessation program within the last 6 months
- severe mental illness
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Cognitive-Behavioral Therapy
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a cognitive-behavioral smoking cessation program; 6, weekly-held, group sessions (90 min each)
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Experimental: Hypnotherapy
|
hypnotherapeutic smoking cessation program; 6, weekly-held, group sessions (90 min each)
Other Names:
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
12-months continuous smoking abstinence according to the Russell Standard (RS; West et al. 2005)
Time Frame: 12-months follow-up
|
12-months follow-up
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
7-day point-prevalence smoking abstinence rates at 6- and 12-months follow-up
Time Frame: 12-months follow-up
|
12-months follow-up
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Study Director: Anil Batra, Prof., University Hospital Tuebingen
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
September 1, 2010
Primary Completion (Actual)
April 1, 2013
Study Completion (Actual)
April 1, 2013
Study Registration Dates
First Submitted
May 24, 2010
First Submitted That Met QC Criteria
May 24, 2010
First Posted (Estimate)
May 25, 2010
Study Record Updates
Last Update Posted (Estimate)
February 4, 2014
Last Update Submitted That Met QC Criteria
February 3, 2014
Last Verified
February 1, 2014
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- DKH-Studie VT-HT
- 108368 (Other Grant/Funding Number: Deutsche Krebshilfe e.V.)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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