Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH)

December 22, 2010 updated by: Umeå University

Evaluation of a Computerised Neuropsychological Test Battery for Idiopathic Normal Pressure Hydrocephalus (INPH)

A computerised neuropsychological test battery to be used as a standardised tool assessing the cognitive domains affected by idiopathic normal pressure hydrocephalus INPH was developed. The aim of this study is to investigate the reliability, validity and feasibility of the battery.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

97

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Sweden
    • Västerbotten
      • Umeå, Västerbotten, Sweden, SE-901 85
        • Department of Clinical Neuroscience

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Reliability: Healthy elderly Validity: Various diseases Feasibility: Possible INPH-patients

Description

Inclusion Criteria:

  • Probable INPH under investigation
  • Healthy elderly
  • Various diseases

Exclusion Criteria:

  • (Healthy elderly) medications affecting nervous system
  • (Healthy elderly)heart disease
  • (Healthy elderly)diabetes
  • (Healthy elderly)disease of the nervous system
  • (Healthy elderly)MMSE < 28
  • (Healthy elderly)vascular risk factors (Two of: 1 hypertension, 2 smoking or 3 hyperlipidemia)
  • (Healthy elderly)serious disease that may shorten life expectancy
  • (Various diseases) Affected motor functions

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Test-retest
Forty-four healthy elderly 60-82 years old
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.
Validity
Twenty six patients with various diseases and various ages
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.
Other: Conventional neuropsychological test
Conventional neuropsychological test (paper and pen)
Feasibility
Twenty seven patients under the preoperative investigation for INPH
Device: Computerized neuropsychological test
Computerized neuropsychological test battery.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Validity
Time Frame: Within 24 h
Computerized test battery and equivalent standard neuropsychological test battery is given to the same subject. Correlation between paper and pen and equivalent computerized test is calculated as a validity measure.
Within 24 h
Reliability
Time Frame: More than 7 days, within 2 months
The computerized test battery is given to the same subject twice. Correlation between the two tests is calculated as a test-retest reliability measure.
More than 7 days, within 2 months
Feasibility
Time Frame: Within 24 h
Patients under the investigation for INPH are given the computerized test battery. Number of patients who manage to complete the test is the feasibility measure.
Within 24 h

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Umeå University

Investigators

  • Principal Investigator: Anders Behrens, M.D., M.Sc., Department of Clinical Neuroscience

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

August 1, 2007

Primary Completion (Actual)

April 1, 2010

Study Completion (Actual)

April 1, 2010

Study Registration Dates

First Submitted

December 21, 2010

First Submitted That Met QC Criteria

December 22, 2010

First Posted (Estimate)

December 23, 2010

Study Record Updates

Last Update Posted (Estimate)

December 23, 2010

Last Update Submitted That Met QC Criteria

December 22, 2010

Last Verified

December 1, 2010

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 07-088M

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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