In Utero Capacity Formation and Socio-economic Outcomes (CDS)

The Contribution of Health in Utero to Capacity Formation, Education and Economic Outcomes: Experimental Evidence From Tanzania

Because of the high returns of schooling in developing countries, policymakers pay a lot of attention to increasing school access. But if the mother is deficient in key micronutrients, brain development can biologically constrain children's demand for education. To execute this strategy, the investigators collect cohort observational data on a previous randomized controlled trial with micronutrient supplements offered to HIV-negative pregnant women in Dar es Salaam, Tanzania, between 2001 to 2003.

Study Overview

• Status: Completed
• Conditions: Folic Acid Deficiency
• Intervention / Treatment: Other: observational follow-up

Detailed Description

This is a cohort study which collected follow-up observational data on households which were offered micronutrient supplements. The followup study outcomes include various socio-economic household characteristics and parental post-natal behaviors.

• Study Type: Observational
• Enrollment (Actual): 4000

Contacts and Locations

Study Locations

• Tanzania
  • Dar es Salaam, Tanzania
    • MUHAS

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 49 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Individuals from a larger study and this study is an observational follow-up.

Description

These were individuals from the larger study and this study is an observational follow-up.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
observational followup; This was an observational follow-up to a larger study in which treatment group was given 20 mg of vitamin B1, 20 mg of vitamin B2, 25 mg of vitamin B6, 100 mg of niacin, 50 μg of vitamin B12, 500 mg of vitamin C, 30 mg of vitamin E, and 0.8 mg of folic acid	Other: observational follow-up; observational follow-up

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Children's Cognitive Development		During 2011-2012 (1 year)
Children's Health	BMI, Disease Incidence, Self-reported health	During 2011-2012 (1 year)
Parental Postnatal Investment Behavior	Outcomes on parental care: care, cognitive stimulation, within-household time and money allocation	During 2011-2012 (1 year)
Educational Status	School attendance, Student performance (at school), Test Performance	During 2011-2012 (1 year)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Parental Labor Force Participation	Parent's labor force outcomes: labor status, wages, type of job	During 2011-2012 (1 year)

Collaborators and Investigators

• Sponsor: Harvard University
• Investigators: Study Director: Plamen Nikolov, Harvard University

Study record dates

Study Major Dates

• Study Start: April 1, 2002
• Primary Completion (Actual): September 1, 2012
• Study Completion (Actual): September 1, 2013

Study Registration Dates

• First Submitted: August 8, 2011
• First Submitted That Met QC Criteria: August 8, 2011
• First Posted (Estimate): August 9, 2011

Study Record Updates

• Last Update Posted (Actual): August 7, 2019
• Last Update Submitted That Met QC Criteria: August 5, 2019
• Last Verified: August 1, 2019

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nutrition Disorders; Avitaminosis; Deficiency Diseases; Malnutrition; Vitamin B Deficiency; Folic Acid Deficiency
• Other Study ID Numbers: F19899-101

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO