Improving Depression Care for Elders: Coordinating Center (IMPACT)

March 26, 2012 updated by: Jurgen Unutzer, MD, MPH, University of California, Los Angeles

This Was a Five-year Seven-site Trial to Study the Cost-effectiveness of a Population Based Disease Management Program for Late Life Depression in Primary Care.

Purpose: To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment(IMPACT) collaborative care management program for late-life depression.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

This study tested an organized method of delivering care for late life depression in primary care. Specifically, the investigators evaluated the effectiveness of this intervention as compared to 'care as usual'. The investigators studied the effect of the intervention on clinical outcomes such as depressive symptoms, functional status, health related quality of life. They also determined the cost-effectiveness of the intervention compared to care as usual.

Study Type

Interventional

Enrollment (Actual)

1801

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

60 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

N/A

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Major depression or dysthymia as diagnosed by a structured diagnostic interview.
  • Patient plans to receive primary care at the study clinic for the next year.

Exclusion Criteria:

  • Age under 60.
  • Current symptoms or history of psychosis or mania as determined by structured diagnostic interview.
  • Cognitive impairment as defined by a score less than 23 on a Mini Mental Status Examination.
  • Terminal illness - defined as having a life expectancy of less than 6 months.
  • Active alcohol abuse as determined by a screening interview.
  • High suicide risk as determined by current plan for suicide or a history of more than 3 prior suicide attempts in the past 10 years.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: IMPACT
Other: IMPACT
IMPACT is a collaborative care management program for late-life depression
Other Names:
  • Improving Mood-Promoting Access to Collaborative Treatment
No Intervention: Care as Usual
Patients received all depression care available to them as part of care as usual in the participating primary care clinics.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Severity of depression symptoms
Severity measured by the 21-item Hopkins Symptom Checklist.

Secondary Outcome Measures

Outcome Measure
Measure Description
Functioning
measured by the Sheehan Health-Related Functioning Index

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of California, Los Angeles

Collaborators

Robert Wood Johnson Foundation
The John A. Hartford Foundation
California HealthCare Foundation
Hogg Foundation

Investigators

  • Principal Investigator: Jurgen Unutzer, MD, MPH, University of Washington

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 1999

Primary Completion (Actual)

June 1, 2004

Study Completion (Actual)

June 1, 2004

Study Registration Dates

First Submitted

March 20, 2012

First Submitted That Met QC Criteria

March 20, 2012

First Posted (Estimate)

March 22, 2012

Study Record Updates

Last Update Posted (Estimate)

March 28, 2012

Last Update Submitted That Met QC Criteria

March 26, 2012

Last Verified

March 1, 2012

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • JAHF 98297

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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