Global Registry for Endovascular Aortic Treatment (GREAT) (GREAT)

February 5, 2026 updated by: W.L.Gore & Associates

'GREAT' Global Registry for Endovascular Aortic Treatment - Outcomes Evaluation

Prospective, observational Registry to obtain data on device performance and clinical outcomes.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Detailed Description

This is a prospective observational cohort Registry designed to obtain data on device performance and clinical outcomes of patients treated with Gore Endovascular Aortic products.

Study Type

Observational

Enrollment (Actual)

4600

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Australia
    • New South Wales
      • Camperdown, New South Wales, Australia
        • Royal Prince Alfred Hospital
  • Brazil
      • Florianópolis, Brazil
        • Coris Medicina Avançada
  • Italy
      • Milan, Italy
        • Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
      • Milan, Italy
        • IRCCS Policlinico San Donato
  • United States
    • Illinois
      • Chicago, Illinois, United States, 60637
        • The University of Chicago Medicine & Biological Sciences
    • Texas
      • Plano, Texas, United States
        • Baylor Research Institute

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Consecutive series of patients who undergo treatment with Gore endovascular aortic products.

Description

Inclusion Criteria:

  • Minimum age required by state regulations
  • Indication for aortic endovascular stent graft repair
  • Signed informed consent

Exclusion Criteria:

  • N/A

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Endovascular aortic repair
Patients treated with Gore Endovascular Aortic Products.
Device: Endovascular aortic repair
Treatment with Gore Endovascular Aortic Products.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
To collect "real world" data on the incidence of serious device events.
Time Frame: Up to 10 years
Up to 10 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

W.L.Gore & Associates

Investigators

  • Principal Investigator: Dennis Gable, MD, Baylor Research Institute
  • Principal Investigator: Ross Milner, MD, FACS, The University of Chicago Medicine & Biological Sciences
  • Principal Investigator: Pierre Galvagni Silveira, MD, PhD, Coris Medicina Avançada
  • Principal Investigator: Steven R Dubenec, MD, Royal Prince Alfred Hospital, Sydney, Australia
  • Principal Investigator: Santi Trimarchi, MD, IRCCS Policlinico S. Donato

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 1, 2010

Primary Completion (Estimated)

June 1, 2027

Study Completion (Estimated)

June 1, 2027

Study Registration Dates

First Submitted

August 3, 2012

First Submitted That Met QC Criteria

August 3, 2012

First Posted (Estimated)

August 7, 2012

Study Record Updates

Last Update Posted (Actual)

February 9, 2026

Last Update Submitted That Met QC Criteria

February 5, 2026

Last Verified

February 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • GRT 10-11

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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