Early Detection of Cognitive Dysfunction in Diabetes

December 9, 2014 updated by: zhipeng xu, Wuhan General Hospital of Guangzhou Military Command

Study of Cognitive Dysfunction and Diabetes

The rate of cognitive decline due to ageing is increased 1.5-fold to 2.0-fold in individuals with type 2 diabetes.There are no established specific treatment measures to prevent or ameliorate cognitive impairments in patients with diabetes. we want to detecte early clinical dementia in diabete.

Study Overview

Status

Unknown

Conditions

Detailed Description

Clinically relevant cognitive decrements in relation to diabetes mainly occur during two crucial periods in life: the period of brain development in childhood, and the period when the brain undergoes neurodegenerative changes associated with ageing.Potential leads for treatment are to optimise glycaemic control and avoid and treat vascular risk factors.we want to detecte early clinical dementia in diabete by MMSE and Olfactory function.

Study Type

Observational

Enrollment (Anticipated)

400

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

  • Name: xuzhipeng Wuqiang lihonghua, doctor
  • Phone Number: 13871168392
  • Email: 21823074@qq.com

Study Locations

  • China
    • Hubei
      • Wuhan, Hubei, China, 430070
        • Recruiting
        • Wuhan General Hospital of Guangzhou Command
        • Contact:
      • Wuhan, Hubei, China, 430074
        • Enrolling by invitation
        • tongji Medical University
      • Wuhan,chongqing, Hubei, China, 430070
        • Active, not recruiting
        • Wuhan General Hospital of Guangzhou Command

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

50 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Patients with type 2 diabetes

Description

Inclusion Criteria:

  • Patients with type 2 diabetes(Age>50 years)

Exclusion Criteria:

  • with stroke or other complications.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
control,MCI, Olfactory dsfunction
There are different groups:control,MCI, Olfactory dsfunction.
control, MCI
control and MCI group.Glycaemic control
control and MCI
treatment and without treatment
MCI and Olfactory function
observation between MCI and Olfactory function groups.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
MMSE Olfactory function dementia
Time Frame: 2 years
MMSE,Olfactory function and PET(fMRI) were observed.
2 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Wuhan General Hospital of Guangzhou Military Command

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2012

Primary Completion (Anticipated)

December 1, 2014

Study Completion (Anticipated)

December 1, 2014

Study Registration Dates

First Submitted

April 1, 2013

First Submitted That Met QC Criteria

April 10, 2013

First Posted (Estimate)

April 12, 2013

Study Record Updates

Last Update Posted (Estimate)

December 10, 2014

Last Update Submitted That Met QC Criteria

December 9, 2014

Last Verified

December 1, 2014

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 20130401 (Sponsor)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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