The Sex Specific Waist Circumference Cut Off Points to Predict Overweight or Obesity

July 31, 2013 updated by: Fahri Bayram, TC Erciyes University

The Cross Sectional Study to Investigate the Waist Circumference Cut Off Points for the Prediction of Overweight and Obesity of the Turkish Adult Population

The waist circumference (WC) cut off levels of the Caucasian people may not represent the characteristics of different ethnic groups. The investigators aimed to determine sex specific WC cut off points to predict obesity, metabolic syndrome and increased cardiovascular risk in Turkish adults.

Study Overview

Status

Completed

Conditions

The Focus of Study is to Determine the Waist Circumference Values to Predict Overweight or Obesity

Detailed Description

Waist circumference (WC) is an easy and reliable measure of visceral adipose tissue and a simple index of cardiovascular risk. The World Health Organization (WHO) reported sex specific WC cut off values for the Caucasian people, named as action levels 1 and 2, to define the overweight or obese people. These cut off values, originally established in a Dutch population, were later adopted by several medical organizations in order to define Metabolic Syndrome. However, these cut off levels may not necessarily represent the characteristics of the other populations. Therefore it is recommended that the sex specific WC cut off points should be established for different ethnic groups.

The investigators aimed to investigate whether the suggested sex specific WC cut off points for the Caucasian adults are appropriate for the Turkish adult population. The secondary aim of the study is to search for better WC cut off points to predict obesity, metabolic syndrome and increased cardiovascular risk in Turkish adult men and women.

Study Type

Observational

Enrollment (Actual)

4310

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

20 years to 85 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

This cross-sectional study was conducted in 24 provinces from the 7 regions of Turkey. Turkish adult males and non-pregnant females were randomly enrolled from both the provincial district centers and villages, considering the demographics, economic, social, and geographical statuses.

Description

Inclusion Criteria:

Adult Male or nonpregnant Female

Exclusion Criteria:

Pregnant females, Subjects younger than 20 or older than 83

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort
Healthy adults living in Turkey The group was enrolled from the 24 provinces of the 7 regions of Turkey. At least 3 provinces were selected from each region by a random sampling method. The populations of these 7 regions were obtained from the records of the 2000 census. The study sample included males and non-pregnant females aged between 20 and 83 years. The populations of city centers, districts, and villages were classified by using the stratified sampling method and then were selected from the data collected from the household identification forms by random sampling. The geography of Turkey was classified into three groups according to altitude. Sea level was accepted as zero. 0-300 m was taken as coastal, 300-900 m as moderate

Group / Cohort

Healthy adults living in Turkey

The group was enrolled from the 24 provinces of the 7 regions of Turkey. At least 3 provinces were selected from each region by a random sampling method. The populations of these 7 regions were obtained from the records of the 2000 census. The study sample included males and non-pregnant females aged between 20 and 83 years. The populations of city centers, districts, and villages were classified by using the stratified sampling method and then were selected from the data collected from the household identification forms by random sampling. The geography of Turkey was classified into three groups according to altitude. Sea level was accepted as zero. 0-300 m was taken as coastal, 300-900 m as moderate

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Waist circumference cut off levels Time Frame: About a year to collect all the demographic data	These cut off levels were determined by the receiver operating curve analyses. The sum of the highest sensitivity and specificity values of the WC levels to determine the overweight (Body mass index (BMI) > 25kg/m2) and obese (BMI>30kg/m2) adults were taken as the cut off points. The cut off points to determine the overweight, were also taken as the WC limits for the diagnosis of metabolic syndrome.	About a year to collect all the demographic data

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

TC Erciyes University

Investigators

Study Director: Fahri Bayram, MD. Prof., Head of the Study Group of Hypertension, Lipid disorders and Obesity of Turkish Society of Endocrinology and Metabolism

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Gundogan K, Bayram F, Gedik V, Kaya A, Karaman A, Demir O, Sabuncu T, Kocer D, Coskun R. Metabolic syndrome prevalence according to ATP III and IDF criteria and related factors in Turkish adults. Arch Med Sci. 2013 Apr 20;9(2):243-53. doi: 10.5114/aoms.2013.34560. Epub 2013 Apr 12.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2003

Primary Completion (Actual)

September 1, 2004

Study Completion (Actual)

September 1, 2005

Study Registration Dates

First Submitted

July 25, 2013

First Submitted That Met QC Criteria

July 31, 2013

First Posted (Estimate)

August 2, 2013

Study Record Updates

Last Update Posted (Estimate)