Autologous Fat Graft Alleviate Scar Pain

October 23, 2013 updated by: Kaohsiung Medical University Chung-Ho Memorial Hospital

Alleviation of Neuropathic Scar Pain With Autologous Fat Graft

Traumatic wounds inflict small- and large-fiber sensory nerve damage, causing neuropathic pain in scar tissue. Autologous fat grafting has been clinically shown to improve scar quality, but scantly study has explored its effects on pain. The aim of the study was to survey its effect on pain.

Study Overview

Status

Completed

Conditions

Detailed Description

Methods: From February 2008 and June 2013, a total of 36 patients received autologous fat grafting in scar areas. Patients who Douleur Neuropathique 4 Questions (scores >4/10) were enrolled this study. The Visual Analogue Scale (VAS), and Neuropathic Pain Symptom Inventory (NPSI) were used to evaluate pain preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks. The mechanism of trauma, duration of allodynia, fat graft volume, and total follow-up time were recorded.

Study Type

Observational

Enrollment (Actual)

36

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Taiwan
      • Kaohsiung City, Taiwan, 80708
        • Kaohsiung Medical University Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

19 years to 75 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

patients received autologous fat grafting in scar areas

Description

Inclusion Criteria:

  • February 2008 and June 2013, patients received autologous fat grafting in scar areas and also had pain over scar area before surgery

Exclusion Criteria:

  • patients refused to participate the study

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
scar, Fat Graft, Visual Analogue Scale
patients received autologous fat grafting in scar areas

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Visual Analogue Scale (VAS)
Time Frame: preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks.
preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks.

Secondary Outcome Measures

Outcome Measure
Time Frame
Neuropathic Pain Symptom Inventory (NPSI)
Time Frame: preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks
preoperatively and postoperatively after 1 week, 4 weeks, and 24 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Kaohsiung Medical University Chung-Ho Memorial Hospital

Investigators

  • Principal Investigator: shu-hung huang, MD, Division of Plastic Surgery, Department of Surgery, Kaohsiung Medical University Hospital
  • Study Chair: Chung-Sheng Lai, PhD, Division of Plastic Surgery, Department of Surgery, Kaohsiung Medical University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

February 1, 2008

Primary Completion (Actual)

January 1, 2013

Study Completion (Actual)

April 1, 2013

Study Registration Dates

First Submitted

October 23, 2013

First Submitted That Met QC Criteria

October 23, 2013

First Posted (Estimate)

October 28, 2013

Study Record Updates

Last Update Posted (Estimate)

October 28, 2013

Last Update Submitted That Met QC Criteria

October 23, 2013

Last Verified

December 1, 2012

More Information

Terms related to this study

Other Study ID Numbers

  • KMUH-IRB-20120246

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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