- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02113345
The Relationship Between Metamemory and Memory in Old Age (M&Mresearch)
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
There are 3 studies in the present research. Study 1 is a reliability and validity study of the Chinese Metamemory Scales. Study 2 is a cross-sectional study to explore the relationship between metamemory and memory of elders encountered in Hong Kong primary health care setting.Study 3 is an Effectiveness Study of Metamemory Cognitive Intervention on elders with mild cognitive impairment and low memory self-efficacy.
This research has the following aims and hypotheses:
Research Aims:
- To evaluate the reliability and validity of the Chinese Metamemory Scales
- To explore the relationship between metamemory and memory of elders
- To evaluate the effectiveness of a metamemory cognitive intervention on Mild Cognitive Impairment (MCI) elders who have low memory self-efficacy
Research Hypotheses:
Study 1: The Chinese Metamemory Scales will show acceptable psychometric properties.
Study 2: There is a positive correlation between metamemory (subjective memory) and memory (objective memory) and this relationship is mediated by stereotyped beliefs about memory ageing.
Study 3: Comparing to Control Group, the Intervention Group will yield the following expected results:
- There is an improvement in objective memory measures post-training.
- There is an improvement in subjective memory measures post-training.
- There is an improvement in mood measures post-training.
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Contacts and Locations
Study Locations
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-
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Hong Kong, Hong Kong
- Research Site
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-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Study 1:
Participants are Chinese elderly of age 65 or above and they speak Cantonese as their primary language. They are to be recruited from a convenience sample of clients who are without cognitive problems and are attending service in the Elderly Health Centres (EHC) of the Elderly Health Service of the Department of Health, Hong Kong Special Administrative Region Government (HKSARG).
- Study 2:
In addition to the inclusion criteria of Study 1, EHC members with confirmed dementia, suspected dementia, and suspected MCI will also be invited to participate in Study 2. However, confirmed demented clients and suspected demented clients must show their capacity to appraise by passing Quality of Life Appraisal Inventory (CapQOL) (Wong, J.G.W.S. et al., 2005) before they are accepted to the Study. All clients are recruited upon consent.
- Study 3:
Suspected MCI participants of Study 2 with below average memory self-efficacy assessed to have MCI (according to operational definition) will be invited and recruited to Study 3 upon consent. In the present research, MCI is defined operationally according to prior local studies and determined with reference to the educational level-adjusted cutoff scores of Chinese Mini Mental Status Examination (CMMSE) and Abbreviated version of Memory Inventory for the Chinese combined (Lam, L. C.W. & et al., 2005; Lam, L.C.W. & et al., 2008).
Exclusion Criteria:
- The presence of currently active medical conditions potentially affecting cognition e.g. vitamin B12 deficiency, hypothyroidism, chronic alcoholism, delirium, and active psychiatric disorders e.g. schizophrenia
- Other conditions that might affect cognitive competency e.g. aphasia, severe visual or hearing impairment.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: lifestyle counseling
Metamemory Cognitive Intervention
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Metamemory Cognitive Intervention
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Objective Memory Measures
Time Frame: Baseline, post-intervention at week 16
|
change from baseline in Hong Kong List Learning Test, 2nd Edition (HKLLT, Chan, A.S., 2006) for verbal episodic memory
|
Baseline, post-intervention at week 16
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|
Objective Memory Measures
Time Frame: Baseline, post-intervention at week 16
|
Change from baseline in Figure Recognition of Memory Assessment Scale (MAS, Williams, 1991) for visual episodic memory
|
Baseline, post-intervention at week 16
|
|
Objective Memory Measures
Time Frame: Baseline, post-intervention at week 16
|
Change from baseline in Category Verbal Fluency Test (CVFT, categories to be chosen with reference to local studies by published by Chiu, H.F.K. et al., 1997 and Mok et al., 2004) for semantic memory
|
Baseline, post-intervention at week 16
|
|
Objective Memory Measures
Time Frame: Baseline, post-intervention at week 16
|
Change from baseline in Digit Span and Visual Spatial Span from (MAS, Williams, 1991) for verbal and visual memory working memory
|
Baseline, post-intervention at week 16
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Objective Memory Measures
Time Frame: Baseline, post-intervention at week 16
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Change from baseline in Event-based and Time-based Tasks for prospective memory (tasks to be developed with reference to the recommendations of Wilson, B.A. & et al., 2008)
|
Baseline, post-intervention at week 16
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Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Subjective Memory Measures
Time Frame: Baseline, post-intervention at week 16
|
Change from baseline in the Chinese version of Memory Self-efficacy Scale (MSE, Frequency of Forgetting-10 Scale, Zelinski and Gilewski, 2004)
|
Baseline, post-intervention at week 16
|
|
Subjective Memory Measures
Time Frame: Baseline, post-intervention at week 16
|
Change from baseline in Chinese versions of the Abbreviated version of Memory Inventory for the Chinese (AMIC, Lam, Linda, C. W. & et al., 2005)
|
Baseline, post-intervention at week 16
|
|
Subjective Memory Measures
Time Frame: Baseline, post-intervention at week 16
|
Change from baseline in Chinese versions of the Anxiety about Memory (AM, a subscale of the Memory Functioning Questionnaire, Gilewski, Zelinski & Schaie, 1990, for Study 1 only)
|
Baseline, post-intervention at week 16
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Subjective Memory Measures
Time Frame: Baseline, post-intervention at week 16
|
Change from baseline in Chinese versions of the Stereotypes about Memory Aging (SMA, Fort & Gana, 2009)
|
Baseline, post-intervention at week 16
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Debbie SK Chow, The University of Hong Kong
Study record dates
Study Major Dates
Study Start
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 082010Deb
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