A Trial on the Opportunity and Treatment of Residual Deformity After Reduction in Developmental Dislocation of the Hip

A Multi-center Study on the Opportunity and Treatment of Residual Deformity After Reduction in Developmental Dislocation of the Hip

Developmental dislocation of the hip is a common disease in children, and its incidence in China is about 9 ‰.The pathological changes of it is complex. The reluxation , subluxation and residual deformity and other complications are relatively common after treatment. The X-ray appears great acetabular index and wide medial gap , small central-edge angle. As there is no effective methods for treating such complications , investigators conducted this trial to find and prove optimal intervention time and treatment programs.

Study Overview

• Status: Not yet recruiting
• Conditions: Reduction; Developmental Dislocation of the Hip; Congenital Dislocation of Hip; Residual Deformity
• Intervention / Treatment: Procedure: Pelvic osteotomy

• Study Type: Observational
• Enrollment (Anticipated): 2

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 1 year to 14 years (CHILD)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

The south of China

Description

Inclusion Criteria:

• The inclusion criteria consists of patients with large acetabular index ,small central-edge angle after reduction in developmental dislocation of the hip

Exclusion Criteria:

• Age >14 years
• Patients are complicated with mental, neurological disorders (such as hypoxic-ischemic encephalopathy, epilepsy and dementia) or significant barriers to growth.
• Patients are complicated with cerebral palsy, multiple joint contractures disease.
• Children are complicated with dysfunction of liver and kidney , blood disorders, immune deficiency disease and ECG abnormalities.
• Parents refused further treatment.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Pelvic osteotomy	Procedure: Pelvic osteotomy

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Early treatment can achieve good results in the residual deformity after reduction in developmental dislocation of the hip	Acetabular index of all ages were measured ，and the acetabular index of patients getting early treatment (pelvis osteotomy ) is normal in all ages according to "The measurements of normal acetabular index and Sharp acetabular angle in Chinese hips" publised on Chinese Journal of Orthopaedics in 2010.	3 years

Collaborators and Investigators

• Sponsor: Hongwen Xu
• Collaborators: Tongji Hospital; Wuhan Union Hospital, China; Hunan Children's Hospital; Shenzhen Children's Hospital; Wuhan Women and Children's Medical Center; Foshan Hospital of Traditional Chinese Medicine

Study record dates

Study Major Dates

• Study Start: September 1, 2014
• Primary Completion (ANTICIPATED): December 1, 2024

Study Registration Dates

• First Submitted: May 6, 2014
• First Submitted That Met QC Criteria: June 11, 2014
• First Posted (ESTIMATE): June 13, 2014

Study Record Updates

• Last Update Posted (ESTIMATE): March 21, 2016
• Last Update Submitted That Met QC Criteria: March 18, 2016
• Last Verified: March 1, 2016

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Wounds and Injuries; Joint Diseases; Musculoskeletal Diseases; Hip Injuries; Musculoskeletal Abnormalities; Congenital Abnormalities; Hip Dislocation; Developmental Dysplasia of the Hip; Hip Dislocation, Congenital; Joint Dislocations
• Other Study ID Numbers: GuangzhouWCMC