- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02393404
Functional Movement-power Training for Children With Developmental Coordination Disorder: A Randomised Controlled Trial
Enhancing Neuromuscular Performance and Central Nervous System Plasticity Through Functional Movement-power Training to Improve Balance Strategies in Children With Developmental Coordination Disorder: A Randomised Controlled Trial
Objective: To compare the effectiveness of functional movement-power training (PT-FMT), functional movement training (FMT) alone and no intervention in improving balance strategies and performance among children with developmental coordination disorder (DCD).
Design: A randomised controlled clinical trial. Sample: 87 children with DCD. Interventions: 12 weeks of PT and FMT or FMT alone in the two intervention groups.
Major outcomes: Sensory organisation test - balance strategy and composite scores; Movement Assessment Battery for Children - total impairment score and balance subscore; hand-held dynamometer measurements of lower limb muscle strength and time to peak force.
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
With the growing numbers of children with dyspraxia in Hong Kong, the focus of paediatric rehabilitation services has shifted from severe motor disorders (e.g., cerebral palsy) to relatively minor motor problems such as developmental coordination disorder (DCD). Evidence-based treatment strategies must be developed to suit this changing need. Children diagnosed with DCD are characterised by marked impairment in motor functions. Poor balance ability is a major concern because it may predispose children to falls and affect their motor skill development. At present, rehabilitation regimes for DCD-affected children use functional movement training (FMT) to induce neural plastic changes in the central nervous system (CNS) and thus enhance functional (balance) performance. Less emphasis is placed on treating the neuromuscular impairments that might also affect functional outcomes. Recently, the investigators research team discovered that slowed hamstring muscle force production, a neuromuscular deficit, may be one of the causes of poor balance strategies in children with DCD, but no effective treatment strategy has yet been examined. Power training (PT) has been found to be effective in increasing the speed of muscle force production and balance in adults through various neuromuscular mechanisms. In this study, the investigators intend to treat both the CNS and peripheral neuromuscular deficits in DCD-affected children. Therefore, the investigators will incorporate PT into a conventional FMT regime. The investigators hypothesise that balance strategies and functional performance in children with DCD will be improved most by treating both the CNS and neuromuscular deficits. This hypothesis will be supported by the finding that PT with FMT is superior to FMT alone in improving balance strategies and functional performance in children with DCD.
Objective: To compare the effectiveness of PT-FMT, FMT alone and no intervention in improving balance strategies and performance among children with DCD. Design: A randomised controlled clinical trial. Sample: 87 children with DCD. Interventions: 12 weeks of PT and FMT or FMT alone in the two intervention groups.
Major outcomes: Sensory organisation test - balance strategy and composite scores; Movement Assessment Battery for Children - total impairment score and balance subscore; hand-held dynamometer measurements of lower limb muscle strength and time to peak force.
Anticipated results and clinical significance: DCD-affected children who receive FMT together with PT will have the best balance performance outcomes. If the results are positive, this training programme could be readily transferrable to clinical practice. This could have positive socio-economic implications, such as shorter treatment periods and reduced healthcare costs.
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
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Pokfulam, Hong Kong
- University of Hong Kong
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-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- a formal diagnosis of DCD based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR)
- a gross motor composite score ≤ 42 on the Bruininks-Oseretsky Test of Motor Proficiency
- 6-10 years old
- attending a mainstream school; and (5) no intellectual impairment.
Exclusion Criteria:
- diagnosis of an emotional, neurological or other movement disorder
- significant congenital, musculoskeletal or cardiopulmonary disorders that might affect motor performance
- receiving active treatments including traditional Chinese medicine
- disruptive behaviour
- unable to follow instructions thoroughly.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: PT-FMT
Functional movement-power training group
|
Physiotherapeutic functional movement-power training
|
Experimental: FMT alone
Functional movement training group
|
Physiotherapeutic power training
|
No Intervention: Control
No intervention control group
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Changes in sensory organisation test balance strategy
Time Frame: Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Changes in sensory organisation test composite scores
Time Frame: Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Changes in Movement Assessment Battery for Children total impairment score
Time Frame: Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Changes in Movement Assessment Battery for Children balance subscore
Time Frame: Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Changes in hand-held dynamometer measurements of lower limb muscle strength
Time Frame: Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Changes in hand-held dynamometer measurements of lower limb muscle time to peak force
Time Frame: Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Baseline (0 month), 3-month post-intervention (3 months), and 3-month follow-up (6 months)
|
Collaborators and Investigators
Sponsor
Publications and helpful links
Study record dates
Study Major Dates
Study Start
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 27100614
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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