The Role of Oxytocin in Modulating the Effects of Social Feedback on Achieving Personal Goals

March 2, 2017 updated by: Keith Kendrick, University of Electronic Science and Technology of China
To examine potential differential effects of receiving various social feedback on achieving personal goals,and whether oxytocin would modulate these effects.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

In the present study, 62 healthy male participants participated in the double-blind, placebo-controlled experiment. Investigators aimed to test the idea that whether oxytocin would modulate subjective responses during receiving various social reward and social punishment about the future outcomes of pursuing personal goals.

Study Type

Interventional

Enrollment (Actual)

62

Phase

  • Early Phase 1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Sichuan
      • Chengdu, Sichuan, China, 610054
        • School of Life science and Technology, University of Electronic Science and Technology of China

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 30 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • Healthy subjects without past or current psychiatric or neurological disorders.

Exclusion Criteria:

  • Taking oral contraceptives;
  • No history of head injury and medical or psychiatric illness.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: oxytocin nasal spray
subjects administrating oxytocin were divided into experimental group
Drug: oxytocin treatment
intranasal administration of oxytocin (40 IU)
Placebo Comparator: placebo nasal spray
subjects administrating placebo were divided into controlled group
Drug: placebo treatment
intranasal administration of placebo (40 IU)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Rating of Encouragement after receiving specific social feedback
Time Frame: one hour
There're 96 different social feedback totally for four goals which were divided into four runs consisting of 24 different feedback separately for each goal video.Therefore,subjects were instructed to complete the encouragement rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum encouragement while nine refers to maximum encouragement.
one hour

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Rating of Likeability after receiving specific social feedback
Time Frame: one hour
There're 96 social feedback totally for four goals which were divided into four runs consisting of 24 feedback separately for each goal video.Therefore,subjects were instructed to complete the likeability rating after receiving each specific feedback. To measure the rating,the investigators used the 9-point likert scale in which one refers to the minimum likeability while nine refers to maximum likeability.
one hour

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Rating of Confidence after receiving a series of social feedback
Time Frame: one hour
There're 96 social feedback totally for four goals which were divided into four runs consisting of 24 feedback separately for each goal video.Furthermore, these 24 feedback were categorized into three types which include 8 feedback separately.Therefore,subjects were instructed to complete the confidence rating after receiving these 8 feedback together. To measure the rating, the investigators used the 9-point likert scale in which one refers to the minimum confidence while nine refers to maximum confidence.
one hour

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Electronic Science and Technology of China

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

November 1, 2014

Primary Completion (Actual)

August 1, 2015

Study Completion (Actual)

October 1, 2015

Study Registration Dates

First Submitted

March 21, 2016

First Submitted That Met QC Criteria

April 14, 2016

First Posted (Estimate)

April 15, 2016

Study Record Updates

Last Update Posted (Actual)

March 6, 2017

Last Update Submitted That Met QC Criteria

March 2, 2017

Last Verified

March 1, 2017

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • UESTC-neuSCAN-14

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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