Combined Resistance and Aerobic Exercise Training on Obesity in Adolescent Girls

Effectiveness of Combined Resistance and Aerobic Exercise Training on Obesity in Adolescent Girls

The purpose of the study was to observe therapeutic effects of combined resistance and aerobic exercise training (CRAE) on hyperinsulemia in obese adolescent girls. Forty obese adolescent girls (14±1 years) participated in this study. The participants were randomly separated into two groups; no-exercise group (n=20) and exercise group (n=20). The exercise group performed 12 weeks of CRAE.

Study Overview

• Status: Completed
• Conditions: Obesity
• Intervention / Treatment: Behavioral: Combined Exercise Training

• Study Type: Interventional
• Enrollment (Actual): 40
• Phase: Not Applicable

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 14 years to 16 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Female

Description

Inclusion Criteria:

• Obese with Hyperinsulinemia
• Obese with Abdominal obesity

Exclusion Criteria:

• Hypertension
• Pregnancy
• Chronic diseases
• Weight loss diet within the last 6 months

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Health Services Research
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: No Exercise (CON); Twenty obese adolescent girls. This arm did not perform any exercise training for 12 weeks. Caloric intake: 1921.7 kcal/day
Experimental: Exercise (EX); Twenty obese adolescent girls. This arm performed combined exercise training 5 times a week for 12 weeks. Caloric intake: 1921.7 kcal/day	Behavioral: Combined Exercise Training; The combined exercise training were consisted with 5 minutes of warm-up, 20 minutes of resistant band exercises (Upper: seated rows, biceps curl, shoulder flexion, elbow flexion, pushup; Lower: hip flexion, hip extension, calf raise, leg press, squat), 30 minutes of treadmill walking, and 5 minutes of cool-down. Intensity of the training was gradually increased from 40-50% heart rate reserve in 1-4 weeks to 60-70% HRR in 9-12 weeks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Height in Meters	Height was measured before and after 12 weeks.	12 weeks
Weight in Kilograms	Weight was measured before and after 12 weeks.	12 weeks
BMI in Weight (Kilograms)/Height (Meters)^2	BMI was calculated with weight and height before and after 12 weeks.	12 weeks
Body Fat in Percents	Body fat was measured before and after 12 weeks.	12 weeks
Lean Body Mass in Percents	Lean body mass was measured before and after 12 weeks.	12 weeks
Waist Circumference in Centimeters	Waist circumference was measured before and after 12 weeks.	12 weeks
Glucose Levels in Millimole Per Liter	Glucose levels were measured before and after 12 weeks.	12 weeks
Insulin Levels in Micro Unit Per Milliliter	Insulin levels were measured before and after 12 weeks.	12 weeks
Homeostasis Model Assessment of Insulin Resistance (HOMA-IR)	Homeostasis model assessment of Insulin Resistance (HOMA-IR) was calculated before and after 12 weeks	12 weeks
Leptin Levels in Nano Grams Per Milliliter	Leptin levels were measured before and after 12 weeks.	12 weeks
Adiponectin Levels in Micro Grams Per Milliliter	Adiponectin levels were measured before and after the training.	12 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Volume of Maximal Oxygen Consumption (VO2max)	Volume of maximal oxygen consumption (VO2max) was determined using a maximal treadmill test before and after 12 weeks.	12 weeks
Arterial Stiffness	Brachial-ankle Pulse Wave Velocity (m/s) was measured using applanation tonometry before and after 12 weeks.	12 weeks
Systolic Blood Pressure	Systolic blood pressure was measured before and after 12 weeks.	12 weeks
Diastolic Blood Pressure	Diastolic blood pressure was measured before and after 12 weeks.	12 weeks
Maximal Heart Rate		12 weeks

Collaborators and Investigators

• Sponsor: Pusan National University
• Collaborators: Dong-Eui University

Study record dates

Study Major Dates

• Study Start (Actual): March 3, 2011
• Primary Completion (Actual): June 3, 2011
• Study Completion (Actual): June 5, 2011

Study Registration Dates

• First Submitted: March 17, 2017
• First Submitted That Met QC Criteria: March 24, 2017
• First Posted (Actual): March 30, 2017

Study Record Updates

• Last Update Posted (Actual): November 3, 2020
• Last Update Submitted That Met QC Criteria: October 30, 2020
• Last Verified: October 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Overnutrition; Nutrition Disorders; Overweight; Body Weight; Obesity
• Other Study ID Numbers: UNOmaha7

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No