Comparison of Aerobic, Resistance, and Combined Training in Overweight/Obese Hypertensive Adults

Compare the Effects of Aerobic, Resistance, and Combined Training in Overweight/Obese Hypertensive Adults

To compare the effects of aerobic, resistance and combined training in hypertensive obese patients

Study Overview

• Status: Completed
• Conditions: Hypertension; Obese
• Intervention / Treatment: Other: Aerobic exercise training Group; Other: Resistance Exercise Training Group; Other: Combined Exercise Training Group

• Study Type: Interventional
• Enrollment (Actual): 63
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Pakistan
  • Azad Jamu Kashmir
    • Kotli, Azad Jamu Kashmir, Pakistan, 11100
      • District Headquarter Hospital - kotli

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 36 years to 66 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Hypertensive with BP greater than 140/90 mmHg
• Overweight and obese adults with BMI (25-40)
• Physically inactive from past 6 months assessed with pedometer. Those with step count of less than 7000 will be included
• To be able to exercise (6MWT),t hose who completed the test without any symptom

Exclusion Criteria:

• Any active systemic illness that restricts exercise
• People doing exercise on regular basis
• Any cardiopulmonary , metabolic and neurological illness

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Aerobic exercise training Group	Other: Aerobic exercise training Group; Aerobic Exercise includes Treadmill walking At Week 1-2, intensity of 40-45% Heart rate maximum (HR max), 3 days/week, for 30 minutes At Week 3-4, intensity of 45-50% HR max, 3 days /week, for 30 minutes At Week 5-6, intensity of 50-60% HR max 3 days per week, for 30 minutes
Experimental: Resistance Exercise Training Group	Other: Resistance Exercise Training Group; Resistive Exercises includes (a) Leg press b) Quadriceps extension c) Bicep curl d) Hip abduction. At Week 1-2, 10 repetitions 1 set, 3 days/week, for 30 minutes At Week 3-4, 2 sets of 10 repetitions, 3 times /week for 30 minutes At week 5-6, 2 sets of 10 repetitions with 5 sec hold 3 times per week for 30 minutes
Experimental: Combined Exercise Training Group	Other: Combined Exercise Training Group; Combined Exercise training includes [Aerobic: Treadmill walking + Resistive Training: a) Leg press b) Quadriceps extension c) Bicep curl d) Hip abduction] Time will be reduced to 15 minutes for both trainings in respective weeks. Aerobic Exercise includes Treadmill walking At Week 1-2, intensity of 40-45% Heart rate maximum (HR max), 3 days/week, for 15 minutes At Week 3-4, intensity of 45-50% HR max, 3 days /week, for 15 minutes At Week 5-6, intensity of 50-60% HR max 3 days per week, for 15 minutes Resistive Exercises At Week 1-2, 10 repetitions 1 set, 3 days/week, for 15 minutes At Week 3-4, 2 sets of 10 repetitions, 3 times /week for 15 minutes At week 5-6, 2 sets of 10 repetitions with 5 sec hold 3 times per week for 15 minutes

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Systolic and diastolic blood pressure	Changes from the Baseline, Blood pressure is measured through sphygmomanometer	6 weeks
Body Mass Index (BMI)	Changes from the Baseline, Body mass index (BMI) will be calculated as weight (kg)/height (m2). Below 18.5 Underweight 18.5 - 24.9 Healthy Weight 25.0 - 29.9 Overweight 30.0 and Above Obesity	6 Week
Change in blood lipid profile	Change in plasma total cholesterol, high density lipoproteins cholesterol (HDL), and low density lipoproteins cholesterol (LDL) after each treatment.	6 Week
Step Count	Pedometer is a valid self-report measure of physical activity. Pedometer is used to count the average daily steps. Change from the baseline to 6 week will be compared.	6 week
Waist circumference	Waist circumference will be measured for abdominal or central fat mass. It is measured in cm at the middle distance between the last floating rib and the iliac crest using a retractable ergonomic measuring tape. Change from the baseline to 6 week will be compared.	6 week

Collaborators and Investigators

• Sponsor: Riphah International University

Study record dates

Study Major Dates

• Study Start (Actual): September 10, 2021
• Primary Completion (Actual): August 30, 2022
• Study Completion (Actual): August 30, 2022

Study Registration Dates

• First Submitted: September 18, 2021
• First Submitted That Met QC Criteria: September 28, 2021
• First Posted (Actual): September 29, 2021

Study Record Updates

• Last Update Posted (Actual): October 24, 2022
• Last Update Submitted That Met QC Criteria: October 21, 2022
• Last Verified: October 1, 2022

More Information

Terms related to this study

• Keywords: Aerobic Exercise; Resistive exercise; Combined Aerobic and Resistive Exercise
• Additional Relevant MeSH Terms: Body Weight; Overweight
• Other Study ID Numbers: REC/01083 Sidra Asghar

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No