Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance

May 18, 2017 updated by: Åsa Håkansson, Lund University

Early Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance in Healthy Adults

Consumption of polyphenol-rich fruits and vegetables may improve the postprandial glucose and insulin responses and hence promote well-being. It has previously been observed that consumption of a bilberry drink decreases the postprandial insulin demand. In the present study, the impact of probiotic fruit beverages with different polyphenol profiles on the postprandial levels of glucose and insulin, were investigated.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

12

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 65 years (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Healthy, not on medication, non-allergic, individuals aged 18-65 years old, having a BMI between 20-30 kg/m2 and also maintaining stable body weight, i.e. less than 5% weight change in the last three months before the study.

Exclusion Criteria:

-

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: SCREENING
  • Allocation: RANDOMIZED
  • Interventional Model: CROSSOVER
  • Masking: QUADRUPLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Bilberry
A bilberry-based beverage with fermented oatmeal
Other: Bilberry
Fruit beverage with bilberry and fermented oatmeal
EXPERIMENTAL: Blackcurrant
A blackcurrant-based beverage with fermented oatmeal
Other: Blackcurrant
Fruit beverage with blackcurrant and fermented oatmeal
EXPERIMENTAL: Mango
A mango-based based beverage with fermented oatmeal
Other: Mango
Fruit beverage with mango and fermented oatmeal
EXPERIMENTAL: Beetroot
A beetroot-based based beverage with fermented oatmeal
Other: Beetroot
Fruit beverage with beetroot and fermented oatmeal
EXPERIMENTAL: Rose hip
A rose hip-based based beverage with fermented oatmeal
Other: Rose hip
Fruit beverage with rose hip and fermented oatmeal
ACTIVE_COMPARATOR: Glucose drink
A reference glucose drink
Other: Glucose drink
A reference glucose drink

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Efficacy of the study products on the postprandial serum insulin
Time Frame: Incremental area under the curve for serum insulin from 0 min up to 120 min following the ingestion of the study product
The postprandial incremental area under the curve for serum insulin
Incremental area under the curve for serum insulin from 0 min up to 120 min following the ingestion of the study product

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Efficacy of the study products on the postprandial serum glucose
Time Frame: Incremental area under the curve for serum glucose from 0 min up to 120 min following the ingestion of the study product
The postprandial incremental area under the curve for serum glucose
Incremental area under the curve for serum glucose from 0 min up to 120 min following the ingestion of the study product

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Lund University

Investigators

  • Study Director: Yvonne Granfeldt, Prof, Lund University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

September 1, 2014

Primary Completion (ACTUAL)

November 1, 2014

Study Completion (ACTUAL)

January 1, 2015

Study Registration Dates

First Submitted

May 17, 2017

First Submitted That Met QC Criteria

May 17, 2017

First Posted (ACTUAL)

May 18, 2017

Study Record Updates

Last Update Posted (ACTUAL)

May 19, 2017

Last Update Submitted That Met QC Criteria

May 18, 2017

Last Verified

May 1, 2017

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • InVeg (1)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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