Patient Trajectories for Older Adults Admitted to Hospital for Alcohol-related Problems

A Multi-centre Registry Study on Patient Trajectories After Interventions for Alcohol-related Health Problems in Somatic Hospital Wards, for People in Late Adulthood (60+)

Alcohol is contributing to many health problems and disorders, as well as accidents and social problems. Alcohol consumption has been on the rise the past 25 years, especially in Norway. The highest increase is found in older adults, in line with the development in most other countries in the western world. Older adults have a higher risk for alcohol related health problems, due to age related physiological changes, medical conditions and medications. Still, alcohol use is seldom addressed for older people. This means that older people rarely receive help to change alcohol habits.

Norwegian health authorities have issued mandates ordering the regional health trusts to implement strategies in somatic hospital wards, mental health services and drug treatment services to identify and treat alcohol and drug problems affecting the patients' health.

In this observational study we will explore patient trajectories three years prior to and three years after an admittance to hospital where risky or harmful alcohol consumption is identified and brief interventions are delivered. Hospitals that have implemented such strategies are invited to the study. Patient trajectories are studied in national health registries. This will provide important knowledge on what characterizes the patients identified, and what happens after they have received a brief intervention related to a hospital admittance.

Study Overview

• Status: Recruiting
• Conditions: Alcohol Dependence; Alcohol; Harmful Use; Alcohol Consumption; Health Risk Behaviors
• Intervention / Treatment: Other: Brief alcohol intervention

Detailed Description

This is a multi-centre registry study in Norwegian medical and surgical hospitals. The project is focusing on patients aged 60+, receiving an intervention for alcohol-related health problems in somatic hospital wards in one year, and without a previous history of referral or treatment in specialized health care for an alcohol or drug problem. Other age groups of adults will be used as control groups. The included patients will also be their own control group, where we compare registry data on the trajectories three years following the alcohol intervention with registry data from the three years preceding the intervention.

The recruited hospitals will have different strategies for identification of and interventions for alcohol-related health problems, and the choice of methods is thus outside of our control. All inhabitants in Norway are registered with a personal identification number. This individual identifier makes the linkage between the participants and the different registries possible. Data from these registries will enable the study of serious incidents, as well as of diagnoses, medications and other treatments, welfare and benefits, and causes of death. Data will be gathered three years retrospectively and 3 years prospectively, related to the index hospital stay where alcohol is addressed and a brief intervention is delivered.

Inclusion criteria for patients are age 21+, no previous treatment history for drug or alcohol problems in specialized health care, admitted to medical or surgical hospital ward, identified risky or harmful alcohol consumption, accepting an alcohol intervention and accepting study participation. Baseline data collected are AUDIT C, question no 10 from the full AUDIT and classification of alcohol consumption (risky or harmful). All other variables are extracted from the national health registries (reimbursement data from primary health care and secondary health care, prescription database, Cause of death registry, Norwegian Trauma Registry and social security data, marital status, professional status).

• Study Type: Observational
• Enrollment (Anticipated): 500

Contacts and Locations

• Study Contact: Name: Torgeir G Lid, MD PhD; Phone Number: +47 48187477; Email: torgeir.gilje.lid@sus.no
• Study Contact Backup: Name: Sverre M Nesvaag, Dr Philos; Phone Number: +47 90837431; Email: sverre.martin.nesvaag@sus.no

Study Locations

• Norway
  • Stavanger, Norway, 4068
    • Recruiting
    • StavangerUH
    • Contact: Torgeir G Lid, MD PhD; Phone Number: +4748187477; Email: torgeir.gilje.lid@sus.no

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 21 years and older (ADULT, OLDER_ADULT)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients 21 years or older admitted to medical or surgical hospital wards offering some kind of screening and brief alcohol intervention as part of the daily routine, and without a prior diagnosis of AUD or SUD.

Description

Inclusion Criteria:

• Age 21 or older, no previous alcohol use disorder or substance use disorder, admitted to hospital which has implemented screening and brief alcohol intervention strategies, written consent to participate

Exclusion Criteria:

• previous alcohol use disorder og drug use disorder

Study Plan

How is the study designed?

Number of groups / cohorts

7

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Age 21-30; Patients aged 21-30 when admitted to hospital and receiving brief alcohol intervention	Other: Brief alcohol intervention; Brief alcohol intervention already implemented in daily routine by the individual hospitals.
Age 31-40; Patients aged 31-40 when admitted to hospital and receiving brief alcohol intervention	Other: Brief alcohol intervention; Brief alcohol intervention already implemented in daily routine by the individual hospitals.
Age 41-50; Patients aged 41-50 when admitted to hospital and receiving brief alcohol intervention	Other: Brief alcohol intervention; Brief alcohol intervention already implemented in daily routine by the individual hospitals.
Age 51-60; Patients aged 51-60 when admitted to hospital and receiving brief alcohol intervention	Other: Brief alcohol intervention; Brief alcohol intervention already implemented in daily routine by the individual hospitals.
Age 61-70; Patients aged 61-70 when admitted to hospital and receiving brief alcohol intervention	Other: Brief alcohol intervention; Brief alcohol intervention already implemented in daily routine by the individual hospitals.
Age 71-80; Patients aged 71-80 when admitted to hospital and receiving brief alcohol intervention	Other: Brief alcohol intervention; Brief alcohol intervention already implemented in daily routine by the individual hospitals.
Age 81 and older; Patients aged 81 and older when admitted to hospital and receiving brief alcohol intervention	Other: Brief alcohol intervention; Brief alcohol intervention already implemented in daily routine by the individual hospitals.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Alcohol use disorder (AUD)	Diagnosis of AUD after recruitment in the study	Three years
Prescriptions for AUD	Prescriptions for the treatment of alcohol use disorder	Three years

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Health care	Diagnoses and procedures in primary and secondary health care	Three years
Trauma	Serious trauma registered in trauma registry	Three years
Death	Death and cause of death	Three years
Prescriptions for addictive drugs	Prescriptions for any drug with addictive potential	Three years

Collaborators and Investigators

• Sponsor: Helse Stavanger HF
• Collaborators: Oslo University Hospital; Sorlandet Hospital HF; Helse Nord-Trøndelag HF; Helse Fonna; Helse Vest; Helse Sor-Ost; Helse Møre og Romsdal HF; Lovisenberg Diakonale Hospital

Study record dates

Study Major Dates

• Study Start (ACTUAL): October 23, 2019
• Primary Completion (ANTICIPATED): December 1, 2024
• Study Completion (ANTICIPATED): December 1, 2025

Study Registration Dates

• First Submitted: November 12, 2019
• First Submitted That Met QC Criteria: November 14, 2019
• First Posted (ACTUAL): November 15, 2019

Study Record Updates

• Last Update Posted (ACTUAL): June 8, 2022
• Last Update Submitted That Met QC Criteria: June 7, 2022
• Last Verified: May 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Chemically-Induced Disorders; Drinking Behavior; Alcohol-Related Disorders; Substance-Related Disorders; Alcohol Drinking; Alcoholism
• Other Study ID Numbers: ID734

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No