Effect of Dual Task on Upper and Lower Extremity Skills in Parkinson's Disease

Examining The Change of Upper and Lower Extremity Skills With The Effect of Dual Task in Parkinson's Disease Patients

The aim of the study is to investigate the change of lower and upper extremity skills with dual task in Parkinson's disease patients and to determine the differences between Parkinson's disease patients with different stages of disease and the healthy controls regarding the change of lower and upper extremity skills with dual task.

Study Overview

• Status: Completed
• Conditions: Parkinson Disease; Movement Disorders
• Intervention / Treatment: Other: Timed Up and Go Test; Other: 10 Meter Walk Test; Other: Purdue Pegboard Test

• Study Type: Observational
• Enrollment (Actual): 45

Contacts and Locations

Study Locations

• Turkey
  • Ankara, Turkey, 06100
    • Hacettepe University, Faculty of Physical Therapy and Rehabilitation

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 36 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Patients with Parkinson's Disease who apply to the Hacettepe University, Faculty of Physiotherapy and Rehabilitation, Department of Neurological Rehabilitation will be invited to this study.

Description

Inclusion Criteria:

• Modified Hoehn & Yahr (H&Y) stages 1 to 3
• at least 40 years of age
• 21 or more MoCA score.

Exclusion Criteria:

• other neurologic disorder
• any orthopedic problem that could prevent to participate in the study
• severe dyskinesia or tremor
• visual or speech problems

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Mild Stage Parkinson's Disease Patients; Modified Hoehn and Yahr stage 1-2	Other: Timed Up and Go Test; It requires individual to stand up from an armed chair, walk 3m, turn around, walk back to the armed chair, and sit down again; Other: 10 Meter Walk Test; 10 Meter Walk Test measures the time required to complete straight walk of 10 meters distance; Other: Purdue Pegboard Test; Purdue Pegboard test evaluates the fine manuel dexterity
Moderate Stage Parkinson's Disease Patients; Modified Hoehn and Yahr stage 2.5-3	Other: Timed Up and Go Test; It requires individual to stand up from an armed chair, walk 3m, turn around, walk back to the armed chair, and sit down again; Other: 10 Meter Walk Test; 10 Meter Walk Test measures the time required to complete straight walk of 10 meters distance; Other: Purdue Pegboard Test; Purdue Pegboard test evaluates the fine manuel dexterity
Healthy Control; Healthy People	Other: Timed Up and Go Test; It requires individual to stand up from an armed chair, walk 3m, turn around, walk back to the armed chair, and sit down again; Other: 10 Meter Walk Test; 10 Meter Walk Test measures the time required to complete straight walk of 10 meters distance; Other: Purdue Pegboard Test; Purdue Pegboard test evaluates the fine manuel dexterity

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Timed Up and Go Test	Functional mobility is assessed by using the timed up and go test. The timed up and go test measures the time that a patient needs to stand up from a chair, walk a 3-m distance, come back and sit back on the chair.	10-15 seconds
10 Meter Walk Test	10 Meter Walk Test measures the time required to complete straight walk of 10 meters distance.	10-15 seconds
Purdue Pegboard Test	Purdue Pegboard Test assesses the speed and motor dexterity of each hand and the manual dexterity using both hands at the same time. The PPT consists of a board with two columns with 25 holes each and a specific number of pins, washers and collars placed in four containers across the top of the board.	3-5 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Modified Hoehn and Yahr Scale	Modified Hoehn and Yahr Scale allocates stages from 0 to 5 to indicate the relative level of disability and stage of disease. Higher level indicates worse physical condition.	1 minute
Montreal Cognitive Assessment (MoCA)	Montreal Cognitive Assessment (MoCA) will be used in order to evaluate cognition. It assesses different cognitive domains: attention and concentration, executive functions, memory, language, visuoconstructional skills, conceptual thinking, calculations, and orientation.It' score ranged from 0 to 30 and higher points indicates better cognitive outcomes.	10-15 minutes
Short-Form 8-Item Parkinson's Disease Questionnaire (PDQ-8)	The short-form 8-item Parkinson's disease Questionnaire (PDQ-8) is the most commonly used scale measuring health related quality of life (HRQoL) in PD patients. It includes 8 items, and each item has five options (never, occasionally, sometimes, often, always or cannot do at all). The total score ranges from 0 to 32. Higher scores indicates poorer quality of life.	1-2 minutes

Collaborators and Investigators

• Sponsor: Hacettepe University

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2020
• Primary Completion (Actual): March 15, 2020
• Study Completion (Actual): August 1, 2020

Study Registration Dates

• First Submitted: February 11, 2020
• First Submitted That Met QC Criteria: February 11, 2020
• First Posted (Actual): February 12, 2020

Study Record Updates

• Last Update Posted (Actual): December 3, 2020
• Last Update Submitted That Met QC Criteria: December 1, 2020
• Last Verified: December 1, 2020

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Parkinsonian Disorders; Basal Ganglia Diseases; Synucleinopathies; Neurodegenerative Diseases; Parkinson Disease; Movement Disorders
• Other Study ID Numbers: 2019/24-01

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No