Acute Effect of Plyometric Exercises on Musculotendinous Properties

Acute Effect of Plyometric Exercises on Musculotendinous Properties of Quadriceps and Biceps Femoral

Preventive and rehabilitation programs include plyometric exercises to promote agility, power, and muscle activation pattern during jumping. These exercises also are known to cause a high mechanical load that increases the risk of a musculoskeletal injury. The knowledge regarding the musculoskeletal damage result from this configuration of exercise can help to elaborate safer and effective training and rehabilitation programs. In this study, the investigators will conduct a clinical trial to determine the acute effect of plyometric exercises on damage caused on different portions of quadriceps and biceps femoral's muscles and tendons of quadriceps, and biceps femoral, and its effects on mechanical properties.

Study Overview

• Status: Unknown
• Conditions: Healthy
• Intervention / Treatment: Other: Plyometric exercises

Detailed Description

This is a single-arm clinical trial aiming to determine the acute effect of one session of plyometric exercises on quadriceps and biceps femoral musculotendinous properties in healthy individuals.

The sample size was determined using G*Power software considering the application of ANOVA: Repeated measures, between factors, 90% power, alpha 0.05. Data from muscle echo intensity of the rectus femoral by Muddle et al. (2019) were considered for this calculation, with an effect size 0.44. A total of 30 individuals was required for this study.

The outcomes will include the muscle and tendon quality, and mechanical properties of the tendon. The assessments will be performed at three different moments: before exercise, immediately after, and 48 hours after exercise.

The data analysis will be performed per protocol. Generalized estimating equations will be used to identify the effects of time followed by Bonferroni posthoc. When effects are found, effect sizes will be estimated. Missing data will be estimated by statistical analysis.

• Study Type: Interventional
• Enrollment (Anticipated): 30
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Brazil
  • RS
    • Uruguaiana, RS, Brazil, 97502772
      • Karine Josibel Velasques Stoelben

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 30 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Who practice physical activity (except jump training);
• No previous lower extremity muscle injury at least 6 months before the recruitment;
• No previous lower extremity ligament or tendon injury or surgery;
• No auditory, vestibular, visual or musculoskeletal injuries or disease that limit the execution of the exercise and assessment protocols;
• No hypertension, cardiovascular, or respiratory disease.

Exclusion Criteria:

• Body mass index greater than 30 kg/m².

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Plyometric exercise	Other: Plyometric exercises; Plyometric exercises will be composed of vertical jumps, box jumps, half squat jumps, high straight jumps, bounding jumps, drop jumps and 10-m sprint.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change from baseline of echo intensity of quadriceps and biceps femoral muscles	Muscle echo intensity will be assessed for transversal and longitudinal ultrasonography images.	Baseline, immediately after exercise and up to 48 hours exercise
Change from baseline stiffness of patellar tendon	Patellar tendon stiffness during 5 seconds rampa contraction protocol. Patellar tendon stiffness will be estimate from force/deformation relationship of tendon.	Baseline, immediately after exercise and up to 48 hours exercise
Change from baseline young modulus of patellar tendon	Patellar tendon young modulus during rampa contraction protocol. Young modulus will be estimate from force/deformation relationship of tendon normalized to transverse section area of tendon.	Baseline, immediately after exercise and up to 48 hours exercise

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change from baseline echo intensity of quadriceps and biceps femoral tendons	Tendons echo intensity will be assessed for transversal and longitudinal ultrasonography images.	Baseline, immediately after exercise and up to 48 hours exercise

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change from baseline muscle soreness of quadriceps and biceps femoral muscles	Soreness will be measure as treashold of pain feeling while a hand-held dynamometer apply force.	Baseline and up to 48 hours exercise

Collaborators and Investigators

• Sponsor: Universidade Federal de Santa Maria
• Collaborators: Federal University of Rio Grande do Sul; Conselho Nacional de Desenvolvimento Científico e Tecnológico
• Investigators: Study Director: Felipe P Carpes, PhD, Universidade Federal do Pampa; Study Chair: Marco A Vaz, PhD, Federal University of Rio Grande do Sul

Study record dates

Study Major Dates

• Study Start (Actual): February 20, 2020
• Primary Completion (Anticipated): October 5, 2021
• Study Completion (Anticipated): March 30, 2022

Study Registration Dates

• First Submitted: February 13, 2020
• First Submitted That Met QC Criteria: February 15, 2020
• First Posted (Actual): February 18, 2020

Study Record Updates

• Last Update Posted (Actual): November 5, 2020
• Last Update Submitted That Met QC Criteria: November 4, 2020
• Last Verified: November 1, 2020

More Information

Terms related to this study

• Keywords: Adult; Lower extermity; Plyometric exercise; Muscle properties
• Other Study ID Numbers: 20180702141429

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: Yes
• IPD Plan Description: The investigators intend to publish the results in an open-access journal, indexed at the Directory of Open Access Journals, with the copyrights transferred to the authors. Details regarding the study's design and statistical plan can be obtained consulting the trial's protocol. Data on other outcomes could be requested contacting the PI.
• IPD Sharing Time Frame: The individual participant dataset will become available at a public repository up to six months after the first study publication
• IPD Sharing Access Criteria: A simple registration will grant access to study datasets. The website for these files is not defined at the time of registration.
• IPD Sharing Supporting Information Type: Study Protocol; Statistical Analysis Plan (SAP); Clinical Study Report (CSR)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No