Treatment of Dentin Hypersensitivity Using Different Desensitizing Agents

April 9, 2020 updated by: ebtsam kassab, Al-Azhar University

The Effect of Using Two Desensitizing Agents Alone and In Combination on Dentin Permeability and Hypersensitivity

Treatment of Dentin Hypersensitivity Using Theobromine , Remin Pro , and Combination of Both Materials

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Anticipated)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Cairo, Egypt, 11111
        • Recruiting
        • Al-Azhar University , Faculty of Dental medicine for Girls
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

14 years to 46 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Patients that aged 18-50 years.
  • Patients in good general health.
  • Patients that have accessible teeth demonstrating signs of sensitivity.

Exclusion Criteria:

  • • Any chronic debilitating disease that could influence study outcomes.

    • Partial dentures, orthodontic appliances, implants or restorations in a poor state of repair that could influence study outcomes.
    • Intolerance or hypersensitivity to the study desensitizing agents or their ingredients.
    • Desensitising treatment or tooth bleaching within 8 weeks of screening.
    • Daily use of medications that might influence the perception of pain.(

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Theobromine
Natural extract from Cocoa
Other: Theobromine
Natural extract from Cocoa
Active Comparator: Remin Pro
Fluoride , Hydroxyapatite , and Xylitol
Other: Remin Pro
Remin Pro
Experimental: Combination
Remin Pro and Theobromine
Other: Theobromine
Natural extract from Cocoa
Other: Remin Pro
Remin Pro

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Visual analogue scale pain score
Time Frame: 1 month
0 = no pain to 10=severe exagerated pain
1 month

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Al-Azhar University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

August 1, 2019

Primary Completion (Anticipated)

August 1, 2021

Study Completion (Anticipated)

April 1, 2022

Study Registration Dates

First Submitted

March 2, 2020

First Submitted That Met QC Criteria

April 9, 2020

First Posted (Actual)

April 10, 2020

Study Record Updates

Last Update Posted (Actual)

April 10, 2020

Last Update Submitted That Met QC Criteria

April 9, 2020

Last Verified

April 1, 2020

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • REC18-145

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Yes

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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