The Study of Anesthesia-related Risk Factors for Postoperative Death in Elderly Non-cardiac Surgery Patients in China

The Study of Anesthesia-related Risk Factors for Postoperative Death in Elderly Non-cardiac Surgery Patients in China: a Multi-center Retrospective Study Based on Database

At present, the elderly population in China has reached 241 million, and there are more than 20 million elderly surgical patients every year, accounting for about 25% of the surgical population. However, there is no research report on the anesthesia related risk factors of death of elderly patients in hospital. The purpose of this study is to analyze the perioperative data of multicenter database, and to explore the anesthesia related death risk factors of elderly patients with noncardiac surgery in the investigator's country, especially within 24 hours after surgery, so as to help improve the anesthesia management technology of elderly patients during surgery, improve the medical quality of perioperative period, and improve the prognosis of patients.

Study Overview

• Status: Enrolling by invitation
• Conditions: Anesthesia; Elderly Patients; Postoperative Mortality; Noncardiac Surgery
• Intervention / Treatment: Other: no interventions

• Study Type: Observational
• Enrollment (Anticipated): 300000

Contacts and Locations

Study Locations

• China
  • Haidian
    • Beijing, Haidian, China, 100853
      • Chinese PLA General Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 65 years and older (Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Since January 2008, all the elderly non-cardiac surgery patients have been treated in these four hospitals in the first medical center of PLA general hospital, henan provincial people's hospital, the second xiangya hospital of central south university, the third xiangya hospital of central south university, and the union medical college hospital affiliated to fujian medical university.

Description

Inclusion Criteria:

• 1.patients larger than 65 years old at the time of surgery 2.Patients hospitalized for surgery between Jua 2008 to April 2020

Exclusion Criteria:

- 1.Critical demographic information and course records are inaccurate or missing.

2.The outcome could not be determined during the hospitalization. 3.Cardiac surgery patients 4.Patients undergoing surgery under local anesthesia

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Retrospective

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Postoperative death	Other: no interventions; no interventions
Postoperative non-death	Other: no interventions; no interventions

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Whether death occurred during hospitalization after surgery	Whether death occurred during hospitalization after surgery	Within 30 days after discharge

Collaborators and Investigators

• Sponsor: Chinese PLA General Hospital

Study record dates

Study Major Dates

• Study Start (Actual): May 31, 2020
• Primary Completion (Anticipated): September 1, 2021
• Study Completion (Anticipated): December 31, 2021

Study Registration Dates

• First Submitted: May 11, 2020
• First Submitted That Met QC Criteria: May 13, 2020
• First Posted (Actual): May 15, 2020

Study Record Updates

• Last Update Posted (Actual): June 9, 2021
• Last Update Submitted That Met QC Criteria: June 8, 2021
• Last Verified: June 1, 2021

More Information

Terms related to this study

• Other Study ID Numbers: PLAGHAOC202001

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No