Effect of Neurodynamics Nerve Flossing on Femoral Neuropathy in Haemophilic Patients

To investigate the effect of Neurodynamics Nerve flossing on femoral neuropathy in patients with haemophilia

Background: heamophilia is one of the serious chronic disorders in children and adolescents which results in less physical activities and restlessness hours than their peer.

HYPOTHESES:

This study will hypnotize that:

Neurodynamics Nerve flossing will have a significant effect on femoral neuropathy in patients with haemophilia

RESEARCH QUESTION:

will the Neurodynamics Nerve flossing has an effect on femoral neuropathy in patients with haemophilia?

Study Overview

• Status: Completed
• Conditions: Femoral Neuropathy in Haemophilic Patients
• Intervention / Treatment: Other: Neurodynamics Nerve flossing; Other: conventional selected exercise program

Detailed Description

Haemophilic patients with Femoral Neuropathy will be randomly divided in two equal groups control group which will receive conventional selected exercise program and study group will receive the same exercise training program in addition to Neurodynamics Nerve flossing three times per week for three successive months.

The Evaluation will done pre and post interventions included:

femoral nerve motor conduction velocity, muscle test For Iliopsoas and Quadriceps muscles and Pain visual analogue scale.

• Study Type: Interventional
• Enrollment (Actual): 30
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • El-Sheikh Zayed City Giza 1133 Egypt
    • Giza, El-Sheikh Zayed City Giza 1133 Egypt, Egypt
      • October 6 University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 8 years to 12 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• hemophilia A or B, all the patients
• positive femoral nerve tension test
• the Manual muscle test for iliopsoas and quadriceps muscles in all patients not less than grade 2 according to the oxford scale
• the age ranging from (12:16) years
• all the participants will be able to communicate verbally ,obey commands and instructions and co-operate with testing and training protocols

Exclusion Criteria:

• any participants have auditory, visual and sever cardiac disorders
• Patients who have mild degree of hemophilia
• Patients who have joint, muscle bleeding or pain in the lower limb in the preceding 3 weeks
• patients with any other neurological disorders or musculoskeletal disorders or deformities of the lower limb.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: study group; received conventional selected exercise program and in addition to Neurodynamics Nerve flossing for femoral nerve	Other: Neurodynamics Nerve flossing; Neurodynamics Nerve flossing for femoral nerve that includes two techniques inform of: "slider technique" and the second is the "tensioner technique; Other: conventional selected exercise program; Ultrasound therapy The flexibility exercises for iliopsoas & quadriceps The iliopsoas & quadriceps muscles strength exercise
Experimental: control group; received conventional selected exercise program in form of: Ultrasound therapy The flexibility exercises for iliopsoas & quadriceps in heamophilic patient The iliopsoas & quadriceps muscles strength exercise	Other: conventional selected exercise program; Ultrasound therapy The flexibility exercises for iliopsoas & quadriceps The iliopsoas & quadriceps muscles strength exercise

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Electromyography Nerve conduction study	Femoral Nerve motor conduction velocity (m/sec.) , via the Neuropack S1 MEB9004 EMG device	12 weeks
Femoral Nerve Tension Test, for femoral nerve injury	Femoral Nerve Tension Test is a neural tension test used to stress the femoral nerve A positive test was be reproduction of the patient's symptoms as burning discomfort in the groin or anterior thigh occurred if there was femoral nerve involvement.	12 weeks
Manual muscle test, Oxford five grades of muscle power assessment	The group Manual muscle test was used for testing the strength of iliopsoas and quadriceps muscles, according to the Oxford Scale as the Muscle strength is often rated on a scale of 0/5 as follow: (0/5) no contraction of muscle, (1/5) muscle flicker contraction, but no movement (2/5) movement possible, but not against gravity (test the joint in its horizontal plane), (3/5) movement possible against gravity, but not against resistance by the therapist, (4/5) movement possible against some resistance by the examiner and (5/5) normal strength	12 weeks

Collaborators and Investigators

• Sponsor: Lama Saad El-Din Mahmoud
• Investigators: Study Director: Lama S Mahmoud, PHD, lecturer , department of Neuromuscular Disorders and its surgery, faculty of physical therapy O6U physical therapy

Study record dates

Study Major Dates

• Study Start (Actual): June 30, 2020
• Primary Completion (Actual): September 30, 2020
• Study Completion (Actual): October 30, 2020

Study Registration Dates

• First Submitted: June 22, 2020
• First Submitted That Met QC Criteria: June 23, 2020
• First Posted (Actual): June 25, 2020

Study Record Updates

• Last Update Posted (Actual): January 6, 2021
• Last Update Submitted That Met QC Criteria: January 5, 2021
• Last Verified: January 1, 2021

More Information

Terms related to this study

• Keywords: Neurodynamics,; Nerve flossing;; femoral neuropathy; , haemophilia,
• Additional Relevant MeSH Terms: Nervous System Diseases; Neuromuscular Diseases; Mononeuropathies; Peripheral Nervous System Diseases; Femoral Neuropathy
• Other Study ID Numbers: P.T./REC /012/002733

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No