Diagnostic Evaluation of Sarcopenia in Elderly Patients

Development of a New Sarcopenia Screening Tool in the Elderly

Sarcopenia is a generalized progressive skeletal muscle disorder that represents a related physiological vulnerability that is associated with or increases the likelihood of adverse outcomes, including falls, fractures, physical disability and death. The parameters used to assess sarcopenia in clinical practice have limited use due to their custody.

In this perspective, this study proposes or develops a tool for the diagnosis of having sarcopenia with a specific boa and a sensitive boa.

low cost and useful.

Elderly patients (n = 403) from the Geriatrics Outpatient Clinic of Hospital das Clínicas, Faculty of Medicine, University of São Paulo will be selected

This study was of clinical importance, due to sarcopenia and a relevant factor, and could lead to consequences and poor prognosis in patients with gold, and it was not a method of clinical practice to properly endorse body composition in this population.

Study Overview

• Status: Completed
• Conditions: Sarcopenia
• Intervention / Treatment: Other

Detailed Description

Sarcopenia is a progressive and generalized skeletal muscle disorder that represents an age-related physiological vulnerability that is associated with an increased likelihood of adverse outcomes, including falls, fractures, physical disability and mortality. The parameters used to assess sarcopenia in clinical practice have limited use due to its cost.

In this perspective, this study proposes the development of a tool for the diagnosis of having sarcopenia with good specificity and good sensitivity and of low cost and useful.

Elderly patients (n = 403) from the Geriatrics Outpatient Clinic of Hospital das Clínicas, Faculty of Medicine, University of São Paulo will be selected. After signing the informed consent, sarcopenia will be assessed using the reference method (DXA) and anthropometry. The data obtained by the methods are treated statistically to obtain correlation and thus a new tool for the evaluation of sarcopenia patients in the elderly can be developed.

This study is of clinical importance, as sarcopenia is a relevant factor and can lead to consequences and poor prognosis in elderly patients, and there is no low-cost method in clinical practice to properly assess body composition in this population.

• Study Type: Observational
• Enrollment (Actual): 403

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 60 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Elderly patients over 60 years old, with cognitive ability and interested in participating in the study

Description

Inclusion Criteria:

• Age ≥ 60 years
• Sign free and informed consent;
• Demonstrate interest, conditions and availability to participate in all procedures included in the study protocol;

Exclusion Criteria:

• Refusal to participate;
• Patients who have not undergone cognitive testing;
• Physical amputation;
• Patients undergoing interventional treatment for sarcopenia;

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Prospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Elderly patients with sarcopenia	Elderly patients with sarcopenia

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Sarcopenia in the elderly	Evaluation of sarcopenia in the elderly	12 months

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Development of a new tool for sarcopenia screening	Development of a new tool for sarcopenia screening	12 months

Collaborators and Investigators

• Sponsor: University of Sao Paulo

Study record dates

Study Major Dates

• Study Start (Actual): May 6, 2016
• Primary Completion (Actual): May 6, 2018
• Study Completion (Actual): December 10, 2019

Study Registration Dates

• First Submitted: June 2, 2020
• First Submitted That Met QC Criteria: June 25, 2020
• First Posted (Actual): June 30, 2020

Study Record Updates

• Last Update Posted (Actual): June 30, 2020
• Last Update Submitted That Met QC Criteria: June 25, 2020
• Last Verified: June 1, 2020

More Information

Terms related to this study

• Keywords: Elderly; Body composition; Sarcopenia
• Additional Relevant MeSH Terms: Nervous System Diseases; Neurologic Manifestations; Neuromuscular Manifestations; Pathological Conditions, Anatomical; Muscular Atrophy; Atrophy; Sarcopenia
• Other Study ID Numbers: SARC-F