Message Framing on Recruiting Rh-D Negative Blood Donors

Effects of Message Framing on Recruiting Rh-D Negative Blood Donors in an Emergency Situation

Rh negative blood group is a rare blood group in China, as it only accounts for 0.3-0.4 percent of the Han population. Therefore, low inventory is often found in blood collection and supply agencies in many regions in China. On July 22, 2020 blood stockpile of O-negative and A-negative in Guangzhou Blood Center reached the warning line, and we took measures for emergency recruitment. O-negative and A-negative blood donors whose last donation dates were between January 1, 2018 and December 31, 2019 were identified and randomly assigned to four groups. Three different recruitment text messages were send three groups. We observed the re-donation rates among four groups within one week.

Study Overview

• Status: Unknown
• Conditions: Blood Donation
• Intervention / Treatment: Other: Gain-framed SMS message; Other: Loss-framed SMS message; Other: Information SMS message

• Study Type: Interventional
• Enrollment (Anticipated): 1082
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Jian OU-YANG; Phone Number: +8615918771924; Email: 434524249@qq.com

Study Locations

• China
  • Guangdong
    • Guangzhou, Guangdong, China, 510095
      • Recruiting
      • Guangzhou Blood Center
      • Contact: Jian OUYANG, Master; Phone Number: 0086 15918771924; Email: 434524249@qq.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 60 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

- O and A Rh- negative blood donors Last donations were between January 1, 2018 and December 31, 2019

Exclusion Criteria:

- With an obviously invalid phone number Serological results of the last donation were positive

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

4

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: Control group; Donors in this group were not received SMS reminders.
Experimental: Gain-frame Message; Short messaging service (SMS) message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to save lives. Thank you for your support. Please bring your identification (ID) card and show this message to our staff. Thank you.	Other: Gain-framed SMS message; Emergency recruitment cell phone short messages that emphasizing donating blood can save patients' lives were sent to donors in this group.
Experimental: Loss-frame Message; SMS message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, but patients with such blood group are in urgent need of blood. If you can, please consider donating blood again to prevent the loss of life. Thank you for your support. Please bring your ID card and show this message to our staff. Thank you.	Other: Loss-framed SMS message; Emergency recruitment cell phone short messages emphasizing that donating blood can prevent patients from death were sent to donors in this group.
Experimental: Information Message; SMS message: Dear group O/A Rh-D negative blood donor: Hello! The inventory of group O/A Rh-D negative blood product is low at present, if you can, please consider donating blood again. Thank you for your support. Please bring your ID card and show this message to our staff. Thank you.	Other: Information SMS message; Emergency recruitment cell phone short messages that only mentioning the low Rh-negative blood stockpile were sent to donors in this group.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Re-donation rate	Intention-to-treat were applied. Re-donation rate was defined as the number of donors in each group divided by donors who re-donated within 7 days.	7 days

Collaborators and Investigators

• Sponsor: Guangzhou Blood Center

Study record dates

Study Major Dates

• Study Start (Actual): July 22, 2020
• Primary Completion (Anticipated): July 29, 2020
• Study Completion (Anticipated): July 30, 2020

Study Registration Dates

• First Submitted: July 21, 2020
• First Submitted That Met QC Criteria: July 21, 2020
• First Posted (Actual): July 24, 2020

Study Record Updates

• Last Update Posted (Actual): July 28, 2020
• Last Update Submitted That Met QC Criteria: July 24, 2020
• Last Verified: July 1, 2020

More Information

Terms related to this study

• Other Study ID Numbers: Recruiting Rh-D- blood donors

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No