Reliability of Ultrasound Examination of the Inferior Caval Vein

Reliability of Ultrasound Examination of the Inferior Caval Vein From Different Views in Critically Ill Patients on Artificial Lung Ventilation

The purpose of this study is to compare validity of examination and measurement of inferior caval vein from different views in critically ill patients on mechanical ventilation.

Study Overview

• Status: Unknown
• Conditions: Transthoracic Echocardiography
• Intervention / Treatment: Diagnostic test: Conventional transthoracic echocardiographic examination at the intensive care unit.

Detailed Description

A maximal and minimal diameter of inferior caval vein will be measured by transthoracic echocardiography in critically ill patients on mechanical ventilation hospitalised in the intensive care unit from four different views:

1. Subcostal view on the inferior caval vein in the long axis,
2. subcostal view on the inferior caval vein in the short axis,
3. right lateral view on the inferior caval vein in the long axis,
4. right lateral view on the inferior caval vein in the short axis.

Comparison between the results of measurements in the subcostal view in the long axis and other views will be performed.

• Study Type: Observational
• Enrollment (Anticipated): 100

Contacts and Locations

Study Locations

• Czechia
  • Usti nad Labem, Czechia, 40113
    • Recruiting
    • Masaryk Hospital Usti nad Labem
    • Contact: Roman Skulec, MD, PhD; Phone Number: 00420777577497; Email: skulec@email.cz

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: N/A
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Adult intensive care unit patients on mechanical ventilation.

Description

Inclusion Criteria:

• Inpatients
• Patients on mechanical ventilation indicated for transthoracic echocardiographic examination

Exclusion Criteria:

• Age <18 years
• Insufficient imaging quality
• Refusal of echocardiographic examination by patient

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Prospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Critically ill patients; Critically ill patients hospitalised in the intensive care unit indicated to echocardiographic examination.	Diagnostic test: Conventional transthoracic echocardiographic examination at the intensive care unit.; Conventional transthoracic echocardiographic examination at the intensive care unit targeted to inferior caval vein examination from different views.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Correlation between maximal and minimal diameter of the inferior caval vein from subcostal and right lateral view	Inferior caval vein measurements are key parameters for assessment of preload and fluid responsiveness	During the intervention

Collaborators and Investigators

• Sponsor: Emergency Medical Service of the Central Bohemian Region, Czech Republic
• Collaborators: Masaryk Hospital Usti nad Labem
• Investigators: Principal Investigator: Roman Skulec, MD, PhD, Masaryk Hospital Usti nad Labem

Study record dates

Study Major Dates

• Study Start (Actual): July 27, 2020
• Primary Completion (Anticipated): May 31, 2021
• Study Completion (Anticipated): July 31, 2021

Study Registration Dates

• First Submitted: July 20, 2020
• First Submitted That Met QC Criteria: July 26, 2020
• First Posted (Actual): July 28, 2020

Study Record Updates

• Last Update Posted (Actual): August 19, 2020
• Last Update Submitted That Met QC Criteria: August 18, 2020
• Last Verified: August 1, 2020

More Information

Terms related to this study

• Other Study ID Numbers: 284/33

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No