Secondary Lymphedema Due to Human Adjuvant Disease
Human Adjuvant Disease as a Cause of Secondary Lower Extremity Lymphedema
| Sponsors |
Lead Sponsor: Hospital Angeles del Pedregal |
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| Source | Hospital Angeles del Pedregal | ||||
| Brief Summary | This observational, descriptive, retrospective study the clinical and imaging findings of 10 lower legs of 5 patients with previous history of injection of modeling substances for cosmetic purposes at buttocks and hips ande developed lower limb edema. Lower limb lymphedema index and lymphoscintigraphy findings were evaluated and reported. |
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| Detailed Description | Lymphoscintigraphy findings were reported with the Transport index (TI), were any value over 5 will represent abnormalities in lymphatic function. |
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| Overall Status | Completed | ||||
| Start Date | March 1, 2017 | ||||
| Completion Date | December 1, 2017 | ||||
| Primary Completion Date | July 1, 2017 | ||||
| Study Type | Observational | ||||
| Primary Outcome |
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| Secondary Outcome |
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| Enrollment | 5 | ||||
| Condition | |||||
| Intervention |
Intervention Type: Diagnostic Test Intervention Name: Lower extremity Lymphoscintigraphy Description: Study of lymphoscintigraphy (LCG) abnormalities in a group of patients with history of infiltration of modeling substances in buttocks and hips and complain about lower extremities edema. LCG was performed and evaluated by a single nuclear medicine specialist through injection of the sulfur nanocolloid Technetium 99m, injected intradermal and interdigital in bilateral toes. Dynamic studies were requested for all patients. Standardized acquisition times at 15, 30, 60 and 120 minutes after injection were taken. The following parameters were considered to obtain the transport index in each pelvic limb: transport kinematics, distribution pattern, index time for the appearance of regional lymph nodes, number and collection of colloids in lymph nodes and presence and quality of the colloid uptake by the lymphatic vessels. Summation of these five components resulted in the transport index, which could range from 0 to 45 points |
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| Eligibility |
Sampling Method: Non-Probability Sample
Criteria:
Inclusion Criteria: - Both sex - Over 18 years old - History of injection of modelling substances for cosmetic purposes - History of lower limb edema Exclusion Criteria: - History of primary lower limb lymphedema - Reject to participate - Confirmed other causes of edema Gender: All Minimum Age: 18 Years Maximum Age: 75 Years Healthy Volunteers: Accepts Healthy Volunteers |
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| Location |
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| Location Countries |
Mexico |
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| Verification Date |
October 2020 |
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| Responsible Party |
Type: Principal Investigator Investigator Affiliation: Hospital Angeles del Pedregal Investigator Full Name: javier lopez Investigator Title: Principal investigator, Plastic and reconstructive surgeon staff, MBA, FACS |
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| Has Expanded Access | No | ||||
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| Patient Data | Yes | ||||
| Study Design Info |
Observational Model: Case-Only Time Perspective: Retrospective |
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