- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04646538
Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography
November 25, 2020 updated by: Noha Mohamed El Kateb, Alexandria University
3 D Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography
3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
REPs were done for 10 mature maxillary necrotic teeth with periapical lesions confirmed by digital periapical radiographs.
Instrumentation was done using Protaper Next till size X3 (size 30).
Pre-operative radiographs also included CBCT scans to measure the 3D volume and area of the periapical lesion to be used as baseline data.
The postoperative radiographic examination included: a) digital periapical radiographs taken at 3,6,9, and 12 months to monitor the lesion through out the follow-up period.
b)CBCT scan to measure quantitatively the volume and area of the periapical lesion after 12 months follow up
Study Type
Interventional
Enrollment (Actual)
10
Phase
- Early Phase 1
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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-
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Alexandria, Egypt
- Alexandria University
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
20 years to 40 years (Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Necrotic Mature Maxillary anterior teeth with periapical lesions.
Exclusion Criteria:
- Patients with mobile and fractured teeth
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: X3 group
|
REPs was done for 10 mature maxillary necrotic teeth with periapical lesions.
Instrumentation was done using Protaper Next system till size X3.
Irrigation with 1.5 % NaOCl was done in the first visit.
in the second visit, bleeding was induced in the canal by irritating the periapical area followed by the application of Biodentine as cervical plug then completion of the coronal restoration.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Measurement the volume of periapical lesion preoperatively and comparing it with the new volume after REPs using cone-beam computed tomography.
Time Frame: 12 months
|
Measuring the volume in mm3
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12 months
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
June 5, 2017
Primary Completion (Actual)
August 20, 2018
Study Completion (Actual)
December 30, 2018
Study Registration Dates
First Submitted
November 18, 2020
First Submitted That Met QC Criteria
November 25, 2020
First Posted (Actual)
November 30, 2020
Study Record Updates
Last Update Posted (Actual)
November 30, 2020
Last Update Submitted That Met QC Criteria
November 25, 2020
Last Verified
November 1, 2020
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 19832009
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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