Prospective Evaluation of the Impact on Patients' Quality of Life of a 12-Week Adapted Physical Activity Program (APA) (APA)

Prospective Evaluation of the Impact on Patients' Quality of Life of a 12-Week Adapted Physical Activity Program (APA) at Institut de Cancerologie de l'Ouest (ICO)

The objective of this study is to evaluate the effects of regular physical practice on fatigue, quality of life and kinesiophobia in patients treated at the ICO in Angers, regardless of the type of cancer and the type of treatment.

Study Overview

• Status: Completed
• Conditions: Sports Physical Therapy
• Intervention / Treatment: Other: Adapted Physical Activity (APA)

Detailed Description

The objective of this study is to evaluate the effects of regular physical practice on fatigue, quality of life and kinesiophobia in patients treated at the ICO in Angers, regardless of the type of cancer and the type of treatment.

A 12-week Adapted Physical Activity program (APA) is proposed to patients included in the study with an assessment of fatigue, quality of life, level of physical activity and kinesiophobia (fear of movement) at the beginning of the study.

A second assessment of fatigue and quality of life will be done during the 6-week management.

At the end of the program, a final evaluation of fatigue, quality of life and kinesiophobia will be done.

• Study Type: Observational
• Enrollment (Actual): 37

Contacts and Locations

Study Locations

• France
  • Angers, France, 49055
    • Institut de cancerologie de l'ouest

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Subjects participating in the ICO's APA program during the enrolment period regardless of the type of cancer and the type of treatment in progress (chemotherapy, radiotherapy, hormone therapy, immunotherapy) who accept to participate to the study.

Description

Inclusion Criteria:

1. Oncological care at the ICO
2. All types of cancer
3. Regardless of the type of treatment (chemotherapy, radiotherapy, hormone therapy, immunotherapy)
4. Age > 18 years old
5. Follow the APA program at the ICO
6. Subject informed of the study

Exclusion Criteria:

1. Contraindication to the practice of sport
2. APA Program outside the ICO
3. Subject opposing the use of his data
4. Minor or adult patient under guardianship or curatorship
5. Pregnant woman
6. Altered general condition

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Quality of Life of Patients Participating in the 12-week Adapted Physical Activity Program.	Describe the evolution of the quality of life of patients being treated for their cancer pathology at the ICO site in Angers, and participating in the 12-week adapted physical activity program at ICO. Quality of life is measured with the FACIT-F Fatigue and Quality of Life Questionnaire. The questionnaire is structured into five sections, each containing between 6 and 13 items. In total, it includes 40 items, each scored from 0 to 4: 0 - Not at all; - A little; - Moderately; - Quite a bit; - Very much By adding up the answers, the score range obtained is: 0 to 160. The higher the score, the less tired the patient is.	12 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Describe Attendance at the APA Program.	The number of sessions is planned by the APA coach at the beginning of the APA program. The number of performed sessions is measured.	12 weeks
Measure the Evolution of Kinesiophobia (Fear of Movement).	Kinesiophobia is measured with the TAMPA Scale for Kinesiophobia (TSK-CF). This scale assesses the kinesiophobia index presented by the patient at the time of the assessment. The higher the score, the greater the level of kinesiophobia. Total score range: 17 to 68. Higher scores indicate greater fear of movement. A score ≥ 40 is considered significant kinesiophobia.	12 weeks
Measure Physical Activity at the Initiation of the APA Program.	The level of physical activity (PA) is assessed using the GPAQ questionnaire. The questionnaire consists of 16 items. Physical activity is expressed in MET-minutes per week (Metabolic Equivalent of Task), calculated from reported activity. Based on the score, three profiles are defined: High; ≥3 days vigorous activity (≥1500 MET-min/week) OR; ≥7 days walking/moderate/vigorous PA (≥3000 MET-min/week) Moderate; ≥20 min vigorous PA / day, ≥3 days/week OR; ≥30 min moderate PA/walking / day, ≥5 days/week OR; ≥5 days mixed activity (≥600 MET-min/week) Low; Does not meet above criteria	Week 0

Collaborators and Investigators

• Sponsor: Institut Cancerologie de l'Ouest
• Investigators: Study Chair: Sophie ABADIE-LACOURTOISIE, MD, Institut de cancerologie de l'ouest

Study record dates

Study Major Dates

• Study Start (Actual): September 14, 2020
• Primary Completion (Actual): March 14, 2021
• Study Completion (Actual): March 14, 2021

Study Registration Dates

• First Submitted: December 1, 2020
• First Submitted That Met QC Criteria: December 14, 2020
• First Posted (Actual): December 19, 2020

Study Record Updates

• Last Update Posted (Actual): January 27, 2026
• Last Update Submitted That Met QC Criteria: January 8, 2026
• Last Verified: May 1, 2021

More Information

Terms related to this study

• Keywords: Quality of life; Fatigue; kinesiophobia; Adapted Physical Activity program (APA)
• Additional Relevant MeSH Terms: Mental Disorders; Phobic Disorders; Anxiety Disorders; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Kinesiophobia; Fatigue
• Other Study ID Numbers: ICO-2020-05

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No