Role of Supermicrosurgical LVA for Lower Limb Lymphedema
The Role of Supermicrosurgical Lymphaticovenous Anastomosis for Lower Limb Lymphedema - A Retrospective Cohort Study
| Sponsors |
Lead Sponsor: Chang Gung Memorial Hospital |
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| Source | Chang Gung Memorial Hospital | ||||
| Brief Summary | Vascularized lymph node flap transfer (VLNT) was believed to be the treatment of choice for moderate-to-severe lymphedema. Recent publications have supported the use of supermicrosurgical lymphaticovenous anastomosis (LVA) for treating severe lymphedema. This study hypothesizes whether LVA can be performed on post-VLNT patients seeking further improvement. |
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| Overall Status | Completed | ||||
| Start Date | August 28, 2020 | ||||
| Completion Date | November 19, 2020 | ||||
| Primary Completion Date | October 5, 2020 | ||||
| Study Type | Observational | ||||
| Primary Outcome |
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| Enrollment | 131 | ||||
| Condition | |||||
| Intervention |
Intervention Type: Other Intervention Name: Vascularized lymph node flap transfer Description: Patients who have received VLNT as their primary treatment but with minimal improvement Arm Group Label: lower limb lymphedema patients Intervention Type: Other Intervention Name: Patients without prior lymphedema surgery Description: Patients without prior lymphedema surgery Arm Group Label: lower limb lymphedema patients |
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| Eligibility |
Sampling Method: Non-Probability Sample
Criteria:
Inclusion Criteria: - From November 2014 to January 2019 - Lower limb lymphedema patients Exclusion Criteria: - Patients who have had previous LVA, liposuction, or excisional therapy such as the Charles procedure were excluded. Gender: All Minimum Age: 20 Years Maximum Age: 100 Years Healthy Volunteers: No |
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| Location |
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| Location Countries |
Taiwan |
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| Verification Date |
January 2021 |
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| Responsible Party |
Type: Sponsor |
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| Has Expanded Access | No | ||||
| Condition Browse | |||||
| Arm Group |
Label: lower limb lymphedema patients Description: This retrospective cohort study enrolled 131 lower limb lymphedema patients including 10 patients who have received VLNT as their primary lymphedema surgery showing minimal post-VLNT improvement (Group I) and 121 patients without previous lymphatic surgery (Group II). |
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| Study Design Info |
Observational Model: Case-Control Time Perspective: Retrospective |
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