Role of Supermicrosurgical LVA for Lower Limb Lymphedema

The Role of Supermicrosurgical Lymphaticovenous Anastomosis for Lower Limb Lymphedema - A Retrospective Cohort Study

Sponsors

Lead Sponsor: Chang Gung Memorial Hospital

Source Chang Gung Memorial Hospital
Brief Summary

Vascularized lymph node flap transfer (VLNT) was believed to be the treatment of choice for moderate-to-severe lymphedema. Recent publications have supported the use of supermicrosurgical lymphaticovenous anastomosis (LVA) for treating severe lymphedema. This study hypothesizes whether LVA can be performed on post-VLNT patients seeking further improvement.

Overall Status Completed
Start Date August 28, 2020
Completion Date November 19, 2020
Primary Completion Date October 5, 2020
Study Type Observational
Primary Outcome
Measure Time Frame
Magnetic resonance volumetry 6 months after LVA
Enrollment 131
Condition
Intervention

Intervention Type: Other

Intervention Name: Vascularized lymph node flap transfer

Description: Patients who have received VLNT as their primary treatment but with minimal improvement

Arm Group Label: lower limb lymphedema patients

Intervention Type: Other

Intervention Name: Patients without prior lymphedema surgery

Description: Patients without prior lymphedema surgery

Arm Group Label: lower limb lymphedema patients

Eligibility

Sampling Method: Non-Probability Sample

Criteria:

Inclusion Criteria: - From November 2014 to January 2019 - Lower limb lymphedema patients Exclusion Criteria: - Patients who have had previous LVA, liposuction, or excisional therapy such as the Charles procedure were excluded.

Gender: All

Minimum Age: 20 Years

Maximum Age: 100 Years

Healthy Volunteers: No

Location
Facility: Kaohsiung Chang Gung Memorial Hospital
Location Countries

Taiwan

Verification Date

January 2021

Responsible Party

Type: Sponsor

Has Expanded Access No
Condition Browse
Arm Group

Label: lower limb lymphedema patients

Description: This retrospective cohort study enrolled 131 lower limb lymphedema patients including 10 patients who have received VLNT as their primary lymphedema surgery showing minimal post-VLNT improvement (Group I) and 121 patients without previous lymphatic surgery (Group II).

Study Design Info

Observational Model: Case-Control

Time Perspective: Retrospective

Source: ClinicalTrials.gov