Clinical Dementia Rating Medical Record (CLIMER)

Reliability of the Clinical Dementia Rating Scale From the Medical Record in Comparison With the Reference Method.

The assessment of severity of the cognitive and functional impairment is essential in the follow-up of patients with neurocognitive disorders and in the assessment of the effectiveness of therapeutics. However, the systematic assessment of the Clinical Dementia Rating (CDR) scale is limited due to the time required to complete it (approximately 45 min to 1 hour). Insofar as studies have shown correspondences between the CDR and scales measuring cognitive and neuropsychological performance, and as part of memory consultations, several functional and neuropsychological scales are systematically administered, we wish to conduct a study validating the feasibility of the CDR based on information already available in the patient's file compared to the evaluation of the CDR by the usual method (face-to-face interview in consultation).

This study should highlight the feasibility of scoring the CDR-SB from the files of patients in memory consultation, first in terms of reliability of the scores obtained compared to the standard evaluation, and on the other hand in terms of organization and duration of administration.

Study Overview

• Status: Recruiting
• Conditions: Clinical Dementia Rating (CDR) From the Analysis of Medical Record; Clinical Dementia Rating (CDR) Face-to-face Interview With the Patient
• Intervention / Treatment: Diagnostic test: CDR assessment face-to-face

• Study Type: Observational
• Enrollment (Anticipated): 144

Contacts and Locations

• Study Contact: Name: Anthony Bathsavanis, Psy D; Phone Number: +33 4 72 432 206; Email: anthony.bathsavanis@chu-lyon.fr
• Study Contact Backup: Name: Virginie Dauphinot; Email: virginie.dauphinot@chu-lyon.fr

Study Locations

• France
  • Villeurbanne, France, 69100
    • Recruiting
    • Hopital des Charpennes
    • Contact: Julien Vernaudon, MD; Phone Number: +33 4 72 432 227; Email: julien.vernaudon@chu-lyon.fr

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 65 years and older (Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

The study will be conducted on the basis of the patient consulting in Memory Consultation, specifically with the information already collected in normal care and the MEMORA cohort.

Description

Inclusion Criteria:

• Patient who has CDR assessment in face-to-face interview during the memory consultation,
• Patient with an isolated cognitive complaint or a neurocognitive disorder
• Patient included in the MEMORA cohort

Exclusion Criteria:

• Patient or caregiver who does not wish their data to be used for research purposes within the framework of the MEMORA cohort.

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Cross-Sectional

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Memory consultation patient; The study will be conducted on the basis of the patient consulting in Memory Consultation, specifically with the information already collected in normal care and the MEMORA cohort.	Diagnostic test: CDR assessment face-to-face; The assessment of the CDR is administered once by a psychologist with the patient and his caregiver.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
CDR Sum of boxes (CDR-SB) score out of 18	The CDR-SB score is obtained in normal condition and on file for the same patients. The CDR-SB score makes it possible to distinguish the following classes: 0 (normal), 0.5-4 (questionable cognitive impairment), 0.5-2.5 (questionable impairment), 3-4 (very mild major TNC or very mild dementia), 4.5- 9 (mild or mild dementia), 9.5-15.5 (moderate dementia), 16-18 (severe dementia). The patient's aptitudes are assessed in 6 different areas: 3 cognitive skills: memory, orientation and judgment, 3 acts of everyday living: participation in collective life, home occupations and hobbies, personal care.	The CDR-SB score is collected at the baseline.

Collaborators and Investigators

• Sponsor: Hospices Civils de Lyon
• Investigators: Study Director: Anthony Bathsavanis, Psy D, Hopital des Charpennes; Principal Investigator: Pierre Krolak-Salmon, MD, Hôpital Edouard Herriot

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2020
• Primary Completion (Actual): October 1, 2020
• Study Completion (Anticipated): December 31, 2022

Study Registration Dates

• First Submitted: February 17, 2021
• First Submitted That Met QC Criteria: February 17, 2021
• First Posted (Actual): February 21, 2021

Study Record Updates

• Last Update Posted (Actual): May 2, 2022
• Last Update Submitted That Met QC Criteria: April 29, 2022
• Last Verified: January 1, 2022

More Information

Terms related to this study

• Keywords: reliability; CDR; memory consultation; patient's file
• Additional Relevant MeSH Terms: Mental Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Neurodegenerative Diseases; Tauopathies; Dementia; Alzheimer Disease
• Other Study ID Numbers: 69HCL20_0508

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No