Home-based Pulmonary Rehabilitation for COPD Patients

June 26, 2025 updated by: Marian Papp, Karolinska Institutet

Objectives The objective of this project is to motivate patients with COPD to incorporate the habit of doing daily mindful physical activity by using the proposed home-based pulmonary rehabilitation program that integrates video guided exercises, activity monitoring daily steps and health coaching. This program will allow patients to complete Pulmonary Rehabilitation (PR) at home and promote behavior change and lead to a more active lifestyle for patients with COPD who have been prescribed PR.

The program will be able to effectively monitor daily step count. A health coach will receive more this detailed data and will guide weekly health coaching sessions designed to increase awareness of the physical activities completed and ignite inner motivation for healthy behaviors.

The proposed PR program is innovative and responds to an unmet need in chronic care for COPD patients in the context of COVID-19 pandemic and it mitigates the common accessibility barriers.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

Specific aims will guide the proposed project:

  • Aim 1: To determine the feasibility of the proposed home-based PR program. We will additionally address adherence and appropriateness of the program.
  • Aim 2: To determine improvements in quality of life and mental health of the proposed home-based PR determined.
  • Aim 3: To evaluate if the average number of daily step counts increase after the home-based PR program

Study Type

Interventional

Enrollment (Estimated)

80

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Sweden
      • Stockholm, Sweden
        • Karolinska Institutet
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

40 years to 100 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Men and women age 40 years and older
  • FEV1 <80% or less (forced expiratory volume in one second) as documented by pulmonary function.
  • Medical diagnosis of COPD, GOLD classification B,D, and C based on symptoms and history of exacerbations.
  • The patients must be able to access a smart-phone or computer tablet with internet service.

Exclusion Criteria:

  • Unable to perform low intensity exercise.
  • Patients with a high likelihood of being lost to follow-up or contact (patients with active chemical dependency), are planning to move, are not living in the healthcare area.
  • Patients with an inability to provide good data or follow commands (patients who are disoriented, have a severe neurologic or psychiatric condition).

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Home based exercise
Home based exercise with health coaching
Behavioral: Home based exercise
Exercise at home and behavioural change to increase daily exercise
No Intervention: Usual care
Usual care, waiting list

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Disease specific quality of life
Time Frame: 8-12 weeks
Chronic Respiratory Questionnaire (CRQ)
8-12 weeks
Modified Medical Research Council Dyspnea scale (mMRC),
Time Frame: 8-12 weeks
Dyspnea
8-12 weeks
COPD assessment Test (CAT)
Time Frame: 8-12 weeks
assess symptoms of breathing
8-12 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
GAD to asses anxiety and depression symptoms
Time Frame: 8-12 weeks
assessing anxiety and depression symptoms
8-12 weeks
Online breathing and mindful movement exercises/ exercise routine
Time Frame: 8-12 weeks
Total time performing the breathing exercises
8-12 weeks
Activity monitoring
Time Frame: 8-12 weeks
number of steps
8-12 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Karolinska Institutet

Collaborators

Mayo Clinic

Investigators

  • Principal Investigator: Marian Papp, PhD, Karolinska Institutet

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

February 1, 2026

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2028

Study Registration Dates

First Submitted

March 24, 2021

First Submitted That Met QC Criteria

March 24, 2021

First Posted (Actual)

March 29, 2021

Study Record Updates

Last Update Posted (Estimated)

July 1, 2025

Last Update Submitted That Met QC Criteria

June 26, 2025

Last Verified

June 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2021-01151:DNR

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on COPD, Chronic Obstructive Pulmonary Disease

Clinical Trials on Home based exercise

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bahamas

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe