- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04822389
Telerehabilitation and Lymphoma Patients
July 19, 2022 updated by: Ladislav Batalik, Brno University Hospital
Effect of the Physical Exercise Training Using Telerehabilitation Among Lymphoma Patients: A Pilot Study
This study aims to examine the feasibility and effect of a home-based short-term telerehabilitation exercise intervention using heart rate monitor and internet platform in patients with lymphoma.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Fifteen lymphoma cancer patients post-treatment (except adjuvant treatment) will be enrolled in the study.
Cardiorespiratory fitness (peak oxygen consumption), adverse events, body composition and adherence to exercise prescription will be evaluated at baseline, 12-week, and year after enrollment.
Study Type
Interventional
Enrollment (Actual)
15
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Brno, Czechia, 62500
- University Hospital Brno
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Lymphoma patients post-treatment (except ongoing adjuvant treatment)
- Post-treatment period not exceeding 3 months
- Internet connection at home
- Literacy with information and communication technology
- Patients who agreed with informed consent
Exclusion Criteria:
- Inability to perform a cardiopulmonary exercise test
- Psychological severe or cognitive disorders
- Contraindications for cardiopulmonary exercise testing
- Other exercise limitations (musculoskeletal disorders)
- Planned intervention or operation
- Participants who are enrolled in or participate in other rehabilitation program
- Participants who plan to be or are included in other studies
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Supportive Care
- Allocation: N/A
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
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Experimental: Home-based telerehabilitation exercise
Exercise training is conducted in the patient's home conditions using modern technology to transfer medical data remotely - the participants receive a heart rate monitor and sensor.
To know what to do and how to exercise, the first (1-2) exercise training sessions will be controlled by the physiotherapist in a rehabilitation clinic in the hospital, who creates individual exercise training for each patient.
The patient's training data will be downloaded and updated regularly via the internet platform and clinicians will evaluate these results and provide patients with telephone feedback.
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Eligible participants will undergo 12 weeks of physical exercise using a heart rate monitor and internet platform at home.
The participants will regularly (minimum once per week) upload the exercise data from the heart rate monitor into the internet platform.
An exercise telerehabilitation session consists of the warm-up phase, aerobic phase (30 - 50 minutes gradually increasing exercise duration; heart rate zone based on baseline cardiopulmonary exercise test) and cool-down phase.
The exercise training period is set to 3 times a week for 12 weeks.
Study participants will receive user guides developed by research team with detailed instructions regarding equipment set-up, training protocol, and contact information.
Also, participants will receive weekly phone calls from week 0 to week 12 to monitor adverse events, encourage compliance and adherence to the study protocol, address any subject questions or concerns, and collect information regarding participants' current symptomatology.
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Cardiorespiratory fitness (CRF)
Time Frame: Change from baseline to 12 weeks and 1-year
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Peak oxygen uptake (VO2peak) during the cardiopulmonary exercise test
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Change from baseline to 12 weeks and 1-year
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Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Body composition (Total muscle mass in kilograms)
Time Frame: Change from baseline to 12 weeks and 1-year
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Total muscle mass is the amount of muscle in body, including skeletal muscles, smooth muscles, and cardiac muscles.
Total muscle mass will be measured by bioelectrical impedance analysis.
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Change from baseline to 12 weeks and 1-year
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Body composition (Body fat mass in kilograms)
Time Frame: Change from baseline to 12 weeks and 1-year
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Body fat mass is the actual weight of fat in body.
Body fat mass will be measured by bioelectrical impedance analysis.
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Change from baseline to 12 weeks and 1-year
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Body composition (Body weight in kilograms)
Time Frame: Change from baseline to 12 weeks and 1-year
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Body weight is the measurement of weight without items located on the person.
Body weight will be measured by bioelectrical impedance analysis.
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Change from baseline to 12 weeks and 1-year
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Incidence of treatment-emergent adverse events assessed by 5 grade scale
Time Frame: Data will be recorded continuously from the baseline to 12 weeks
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Participants will be encouraged to use the contact details for reporting the incidence of treatment-emergent adverse events at any time throughout the study period.
The type, incidence, and severity of adverse events by scale (Grade 1: Mild, asymptomatic or mild symptoms; Grade 2: Moderate, minimal; Grade 3: Severe or medically significant; Grade 4: Life-threatening consequences; and Grade 5: Death) will be noted
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Data will be recorded continuously from the baseline to 12 weeks
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Exercise adherence
Time Frame: 12 weeks
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Exercise adherence is defined as number of exercise sessions attended of a possible 36 offered by the exercise intervention program.
Exercise adherence will be determined by participant exercise web datasheet review at 12 weeks.
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12 weeks
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Exercise compliance
Time Frame: 12 weeks
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Number of participants who attend atleast 70% of prescribed exercise sessions measured by exercise datasheet at 12 weeks.
(70% of prescribed exercise sessions = 25 exercise sessions in 12 weeks)
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12 weeks
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
April 1, 2021
Primary Completion (Actual)
April 26, 2022
Study Completion (Actual)
May 31, 2022
Study Registration Dates
First Submitted
March 26, 2021
First Submitted That Met QC Criteria
March 26, 2021
First Posted (Actual)
March 30, 2021
Study Record Updates
Last Update Posted (Actual)
July 20, 2022
Last Update Submitted That Met QC Criteria
July 19, 2022
Last Verified
July 1, 2022
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- IPRHO-KOREHAB2021
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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