Feasibility of Whole-body Drumming Classes for People With Parkinson's Disease

Feasibility and Effects of Whole-body Drumming Classes on Walking in People With Parkinson's Disease: a Pilot Study

People with Parkinson's disease (PD) experience difficulty with gait, postural instability, and lack of movement coordination and rhythmic timing. Non-motor functions affected by PD include time perception, feelings of apathy, depression, decreased self-efficacy, and decrease self-reported quality of life. There is currently a lack of information on how a therapeutic drumming class that uses whole-body large-amplitude movements to music would impact these motor and non-motor impairments in individuals with PD. The primary purpose of this study is to assess the feasibility of a 10-week whole-body drumming class to music specifically selected for its rhythmic structure, and effects on movement rhythm and time perception in individuals with PD. The secondary purpose is to assess the effects of the drumming class on apathy, depression, self-efficacy and health-related quality of life. Participants will be included if they have a diagnosis of PD and are able to move for an hour with rests, either standing or seated. Participants are tested before and after the class series and one month following.

Study Overview

• Status: Active, not recruiting
• Conditions: Parkinson Disease
• Intervention / Treatment: Other: exercise

• Study Type: Interventional
• Enrollment (Anticipated): 25
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Arizona
    • Mesa, Arizona, United States, 85206
      • A.T. Still University Arizona School of Health Sciences

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 21 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• diagnosed with PD
• independent walking short community and household distances with or without assistive device
• able to participate in a 1-hour class once a week for ten weeks

Exclusion Criteria:

• change of Parkinson's medication or deep brain stimulation parameters within 2 weeks prior to or during the study
• inability to grasp 2-inch diameter "drum sticks"
• any conditions with contraindications to lift upper extremities overhead
• any medical restrictions to exercise

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Single Group; A single group of subjects with pretest, posttest, and one-month follow-up testing relative to 10-week drumming exercise classes	Other: exercise; 10 weekly hour-long classes of drumming to music using large-amplitude, whole-body movements

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Step Cadence Variability	Variability (SD) of step cadence	within 7 days before the intervention
Step Cadence Variability	Variability (SD) of step cadence	within 7 days after intervention
Step Cadence Variability	Variability (SD) of step cadence	1-month following intervention
Stride Length Variability	Variability (SD) of stride length	within 7 days before the intervention
Stride Length Variability	Variability (SD) of stride length	within 7 days after intervention
Stride Length Variability	Variability (SD) of stride length	1-month following intervention
Change in repeated finger-tapping	change in inter-tapping intervals (ms) change from pre- to post-intervention	within 7 days before the intervention and within 7 days after intervention
Change in repeated finger-tapping	change in inter-tapping intervals (ms) change from pre- to 1-month following end of intervention	within 7 days before the intervention and 1-month following end of intervention

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Change in Nine-hole peg test (NHP) duration (s)	change in speed of manual dexterity (s on NHP) from pre- to post-intervention	within 7 days before the intervention and within 7 days after intervention
Change in Nine-hole peg test (NHP) duration (s)	change in speed of manual dexterity (s on NHP) from pre- to 1-month following end of intervention	within 7 days before the intervention, and 1-month following intervention
Change in Physical Performance Test (PPT) score	change in whole-body functional mobility (PPT score; 0-36; higher is better) from pre- to post-intervention.	within 7 days before the intervention and within 7 days after intervention
Change in Physical Performance Test (PPT) score	change in whole-body functional mobility (PPT score; 0-36; higher is better) from pre- to 1-month following end of intervention	within 7 days before the intervention, and 1-month following intervention
Change in Parkinson Disease Questionnaire (PDQ-39)	change in disease-related quality of life (PDQ-39 score; 0-100, lower is better with improved quality of life) from pre- to post-intervention	within 7 days before the intervention and within 7 days after intervention
Change in Parkinson Disease Questionnaire (PDQ-39)	change in disease-related quality of life (PDQ-39 score; 0-100, lower is better with improved quality of life) from pre- to 1-month following end of intervention	within 7 days before the intervention, and 1-month following intervention
Geriatric Depression Scale (GDS)	change in depression (GDS score; 0-15, higher is worse with more depression) from pre- to post-intervention	within 7 days before the intervention and within 7 days after intervention
Geriatric Depression Scale (GDS)	change in depression (GDS score; 0-15, higher is worse with more depression) from pre- to 1-month following end of intervention	within 7 days before the intervention, and 1-month following intervention
General Self-Efficacy scale (GSE)	change in self-efficacy (GSE score; 10-40, higher is better with more self-efficacy) from pre- to post-intervention	within 7 days before the intervention and within 7 days after intervention
General Self-Efficacy scale (GSE)	change in self-efficacy (GSE score; 10-40, higher is better with more self-efficacy) from pre- to 1-month following end of intervention	within 7 days before the intervention, and 1-month following intervention
Lille Apathy Rating Scale (LARS)	change in apathy (LARS score; -36 to +36, lower is better with less apathy) from pre- to post-intervention	within 7 days before the intervention and within 7 days after intervention
Lille Apathy Rating Scale (LARS)	change in apathy (LARS score; -36 to +36, lower is better with less apathy) from pre- to 1-month following end of intervention	within 7 days before the intervention, and 1-month following intervention

Collaborators and Investigators

• Sponsor: A.T. Still University of Health Sciences
• Investigators: Principal Investigator: Tara L McIsaac, PhD, PT, A.T. Still University

Study record dates

Study Major Dates

• Study Start (Actual): February 22, 2019
• Primary Completion (Anticipated): July 30, 2022
• Study Completion (Anticipated): July 30, 2022

Study Registration Dates

• First Submitted: May 18, 2021
• First Submitted That Met QC Criteria: July 19, 2021
• First Posted (Actual): July 29, 2021

Study Record Updates

• Last Update Posted (Actual): January 27, 2022
• Last Update Submitted That Met QC Criteria: January 26, 2022
• Last Verified: January 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Parkinsonian Disorders; Basal Ganglia Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Parkinson Disease
• Other Study ID Numbers: 2019-004

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No