Effects of Electromagnetic Field and Noise on Resting Electroencephalogram of Health Subjects

Effects of Electromagnetic Field and Noise on Alpha Band and Functional Connections of Human Resting Electroencephalogram

With the development of science and technology, there are more and more electromagnetic and noise factors in the working and living environment. These two factors often exist together, and their impact on people may interact. Scalp EEG is a classic nerve detection technology, which can reflect the functional state of the brain in a non-invasive and real-time manner. This project intends to use EEG technology to study the effects of electromagnetism and noise on human brain function.

Study Overview

• Status: Completed
• Conditions: Noise Exposure; Electroencephalography; Electromagnetic
• Intervention / Treatment: Other: noise expose; Other: RF expose

• Study Type: Interventional
• Enrollment (Actual): 128
• Phase: Not Applicable

Contacts and Locations

Study Locations

• China
  • Shanxi
    • Xi'an, Shanxi, China
      • Air Force Military Medical University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 30 years (Adult)
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Male, 18-30 years old, right-handed, with normal hearing and normal visual or corrected acuity;

Exclusion Criteria:

• Have history of smoking, alcohol abuse, no history of neurological or psychiatric disorders (e.g., epilepsy), no relevant family history, and no recent medication use;
• Have history of surgery for head injury, no metal implants in the body (including braces);
• Sleep-wake time irregular， with sleep disturbance;
• Have history of noise allergy;
• Participate in similar psychological experiments during 2 months.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: None (Open Label)

Number of Arms

4

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: noise(low-level) and RF(low-level)	Other: noise expose; simulate noise expose environments; Other: RF expose; simulate RF expose environments
Active Comparator: noise(high-level) and RF(low-level)	Other: noise expose; simulate noise expose environments; Other: RF expose; simulate RF expose environments
Active Comparator: noise(high-level) and RF(high-level)	Other: noise expose; simulate noise expose environments; Other: RF expose; simulate RF expose environments
Active Comparator: noise(low-level) and RF(high-level)	Other: noise expose; simulate noise expose environments; Other: RF expose; simulate RF expose environments

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
alpha band power of the EEG spectral	Procedure (record EEG during the noise and RF expose, and then compute the alpha band power of the EEG )
theta band power/beta band power of the EEG spectral	Procedure (record EEG during the noise and RF expose, and then compute theta/beta of the EEG )

Collaborators and Investigators

• Sponsor: Xijing Hospital

Study record dates

Study Major Dates

• Study Start (Actual): November 6, 2021
• Primary Completion (Actual): October 15, 2022
• Study Completion (Actual): November 15, 2023

Study Registration Dates

• First Submitted: December 22, 2021
• First Submitted That Met QC Criteria: January 7, 2022
• First Posted (Actual): January 11, 2022

Study Record Updates

• Last Update Posted (Actual): April 23, 2024
• Last Update Submitted That Met QC Criteria: April 22, 2024
• Last Verified: December 1, 2021

More Information

Terms related to this study

• Keywords: Electroencephalography; Noise Exposure; electromagnetic Exposure
• Other Study ID Numbers: KY20212098-F-1

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No