Red Blood Cell Distribution Width and Charlson Comorbidity Indeces in the Frail Polytraumatized Patient.

RDW and CCI in the Frail Polytraumatized Patients. A Retrospective Cohort Study in a Level 1 Trauma Center.

In this study patients who were admitted to our hospital with critical injuries were enrolled retrospectively from January 2012 to December 2015. Patients with an ISS>16 points, an AIS >3 in one body region and at least 2 different body regions affected were included. RDW values on admission as well as preexisting comorbidities were evaluated.

Study Overview

• Status: Completed
• Conditions: Polytrauma; Comorbidities and Coexisting Conditions; Red Blood Cell Distribution Width
• Intervention / Treatment: Other: retrospective

• Study Type: Observational
• Enrollment (Actual): 400

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Retrospective analysis of polytraumatized patients.

Description

Inclusion Criteria:

• ISS >16 points
• AIS >3 in one body region
• at least 2 body regions affected

Exclusion Criteria:

• patients younger than 18 years of age
• isolated traumatic brain injury
• minor injuries (AIS <3 or ISS <16 points)

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
polytraumatized patients; Patients with an ISS >16 points, an AIS >3 in one body region and at least 2 different body regions affected were included.	Other: retrospective; The investigators retrospectively analyzed the short- and long-term outcome in polytraumatized patients and the possible influence of RDW values on admission as well as preexisting comorbidities on these outcomes.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
In-hospital mortality in polytraumatized patients	January 2012 to December 2015

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Possible influence of RDW values (%) on admission on the long-term outcome	The influence of RDW Values (%) in polytraumatized patients on admission on the long-term outcome (late-phase death (days)) will be examined.	January 2012 to December 2015

Collaborators and Investigators

• Sponsor: Medical University of Vienna

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2012
• Primary Completion (Actual): December 1, 2015
• Study Completion (Actual): December 1, 2015

Study Registration Dates

• First Submitted: January 8, 2022
• First Submitted That Met QC Criteria: January 21, 2022
• First Posted (Actual): February 3, 2022

Study Record Updates

• Last Update Posted (Actual): February 3, 2022
• Last Update Submitted That Met QC Criteria: January 21, 2022
• Last Verified: January 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Wounds and Injuries; Multiple Trauma
• Other Study ID Numbers: RDW Polytrauma

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No