Ultrasonographic Predictors of Hypotension After Induction

Pre-operative Ultrasonographic Evaluation of Inferior Vena Cava Collapsibility Index and Caval Aorta Index to Predict Hypotension After Induction of General Anesthesia

The purpose of the study is to evaluate the predictive value of the inferior vena cava collapsibility index and caval aorta index for detecting hypotension after induction of general anesthesia.

Study Overview

• Status: Completed
• Conditions: General Anesthesia; Hypotension on Induction
• Intervention / Treatment: Other: Inferior vena cava-Aorta diameter index

Detailed Description

Since cardiovascular depressant and vasodilatory effects of anesthetic agents, patients may be at risk of hypotension after induction of general anesthesia. Previous studies reported that, for evaluating volume status, some ultrasonographic measurements such as inferior vena cava collapsibility index (IVCCI) could be used. Also some studies stated that measurement of aorta diameter index (IVC : Ao index) is reliable to predict hypotension after induction of spinal anesthesia. At the study, the investigators aimed to investigate the predictive values of the inferior vena cava collapsibility index and caval aorta index under ultrasound guidance in predicting post-induction hypotension in patients under general anesthesia.

• Study Type: Observational
• Enrollment (Actual): 100

Contacts and Locations

Study Locations

• Turkey
  • Antalya, Turkey
    • Antalya Training and Researching Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 75 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

patients who scheduled for elective non-cardiac surgery under general anesthesia

Description

Inclusion Criteria:

• patients more than 18 years of age
• American Society of Anesthesiologists' (ASA) physical status 1 or 2

Exclusion Criteria:

• BMI more than 30 kg/m²
• Use of angiotensin converting enzyme inhibitors
• pregnancy,
• emergency operations
• baseline arterial systolic blood pressure less than 90 mmHg
• mean arterial blood pressure less than 70 mmHg

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Diagnostic value of IVCCI to detect post-induction hypotension assessed by Receiver operating characteristic (ROC) curve analysis.	Measurement of inferior vena cava collapsibility index.	20 minutes
Diagnostic value of IVC : Ao index to detect post-induction hypotension assessed by ROC curve analysis.	Measurement of inferior vena cava-Aorta diameter index.	20 minutes

Collaborators and Investigators

• Sponsor: Antalya Training and Research Hospital
• Investigators: Principal Investigator: Enes Eskin, M.D., Antalya Training and Research Hospital

Study record dates

Study Major Dates

• Study Start (Actual): March 2, 2022
• Primary Completion (Actual): November 9, 2022
• Study Completion (Actual): November 12, 2022

Study Registration Dates

• First Submitted: January 19, 2022
• First Submitted That Met QC Criteria: February 1, 2022
• First Posted (Actual): February 14, 2022

Study Record Updates

• Last Update Posted (Actual): November 28, 2022
• Last Update Submitted That Met QC Criteria: November 24, 2022
• Last Verified: January 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Hypotension
• Other Study ID Numbers: AntalyaTRH55

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No