Efficacy of TEAS On Prevention of Propofol Injection Pain in Children

April 3, 2026 updated by: Betul Kozanhan, Konya Meram State Hospital

Efficacy of Transcutaneous Electrical Acupuncture Point Stimulation (TEAS) for the Prevention of Propofol Injection Pain in Children

The purpose of this study is to determine the efficacy of transcutaneous electrical acupoint stimulation for the prevention of propofol injection pain in children.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Pain from the injection of propofol is a common side effect during anesthetic practice. Various methods have been used to reduce this pain. This prospective, randomized study was designed to determine the efficacy of transcutaneous electrical acupuncture point stimulation in reducing propofol injection pain in children.

Study Type

Interventional

Enrollment (Actual)

60

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

6 years to 13 years (Child)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • ASA I-II and aged 6-13 years patents who will undergo elective surgery under general anesthesia

Exclusion Criteria:

  • patients with propofol allergy
  • patients who have renal, hepatic, cardiac, neurological, psychiatric disease
  • Cardiac and cranial surgery
  • Pacemaker,
  • Emergency surgery and patients requiring rapid serial induction

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: GROUP TEAS
Patients will receive TEAS bilaterally at two acupoints: Hegu (L14) and Neiguan (PC6).
Device: TEAS
Transcutaneous electrical acupuncture stimulation
Placebo Comparator: Control Sham Group
Patients in the sham group will be undergoing electrode attachment on the target acupoints without electronic stimulation.
Device: TEAS
Transcutaneous electrical acupuncture stimulation

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Pain with propofol injection
Time Frame: 5 minutes
pain will be assessed using a four point behavioral scale: 1= no pain (no reaction); 2= mild pain (grimace); 3= moderate pain (grimace+cry); 4= severe pain (cry+withdrawal)
5 minutes

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Konya Meram State Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

February 14, 2025

Primary Completion (Actual)

August 26, 2025

Study Completion (Actual)

August 26, 2025

Study Registration Dates

First Submitted

March 14, 2022

First Submitted That Met QC Criteria

March 24, 2022

First Posted (Actual)

March 25, 2022

Study Record Updates

Last Update Posted (Actual)

April 9, 2026

Last Update Submitted That Met QC Criteria

April 3, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • TEAS Propofol Injection Pain

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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