The Effects of Hamstring Stretching With and Without Neural Load on Flexibility, Maximum Isometric Strength and Tibial Nerve Pressure Pain Threshold

The Effects of Neural Load on Hamstring Stretching Upon Range of Motion, Maximum Isometric Strength and Tibial Nerve Pressure Pain Threshold in Asymptomatic Patients

The study will be carried out at the Faculty of Nursing and Physiotherapy of the University of Alcala. The study has been approved by the Animal Research and Experimentation Ethics Committee of the University of Alcalá. Healthy subjects will be recruited and divided into two groups randomly to perform a hamstring stretching program for two months.

One group will perform a stretch with neural load and the other without neural load, although both groups will stretch for the same amount of time, repetitions and subjective sensation.

Participants will be measured before and after performing their assigned stretch. Then, a new post-stretch measurement will be taken after two months, period during which the subjects will perform the stretching program on their own. Finally, subjects will be asked to quit the stretching program to take a final evaluation measurement after one month of follow-up.

The objective will be to evaluate the effects of stretching with and without neural load on hamstring flexibility (main variable), maximum isometric strength and tibial nerve pressure pain threshold.

Study Overview

• Status: Completed
• Conditions: Healthy
• Intervention / Treatment: Other: Hamstring stretching program with neural load; Other: Hamstring stretching program without neural load

• Study Type: Interventional
• Enrollment (Actual): 80
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Spain
  • Madrid
    • Alcalá De Henares, Madrid, Spain, 28805
      • Juan

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 50 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Healthy subjects who do not perform hamstring stretches with neural load in their daily training routine

Exclusion Criteria:

• Elite athletes competing or preparing for competition
• Lower limb surgery
• Hamstring injury in the last year
• Neurological, rheumatologic and/or orthopedic pathological history of lower limbs.
• Other comorbidities

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Intervention group; Hamstring stretching program with neural load	Other: Hamstring stretching program with neural load; Participants will perform a hamstring stretch with neural load on their dominant leg. They will stretch five days a week, carrying out two repetitions of one minute each, taking a thirty second break in between. The stretch will be performed in a standing position with their dominant leg on a surface at a mid-thigh height approximately, where their knee is not fully stretched and remains unlocked and their back is in a neutral position. Participants will be encouraged to keep a maximum stretching sensation without feeling any pain. To perform the stretch, different tension parameters will be added in the following order (the next parameter shall not be introduced until the previous one has been exhausted): ankle dorsiflexion, cervical and craniocervical flexion, and hip flexion.
Experimental: Control group; Hamstring stretching program without neural load	Other: Hamstring stretching program without neural load; Participants will perform a hamstring stretch without neural load on their dominant leg. They will stretch five days a week, carrying out two repetitions of one minute each, taking a thirty second break in between. The stretch will be performed in a standing position with their dominant leg on a surface at a mid-thigh height approximately, where their knee is not fully stretched and remains unlocked and their back is in a neutral position. Participants will be encouraged to keep a maximum stretching sensation without feeling any pain. To perform the stretch, tension will be added by flexing their hip, keeping their ankle relaxed and their spine neutral.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Changes in hamstring flexibility	measured with a goniometer. The subject remains in a supine position with both lower limbs extended. One examiner maintains a 90° hip flexion of the lower limb chosen for measurement, while the other examiner passively brings the knee to extension until a greater tissue resistance is noted or a feeling of discomfort is indicated by the subject. The knee extension is measured taking as reference the articular interline, the peroneal malleolus and the greater trochanter. The ankle remains in a relaxed position and the first examiner checks that no pelvic tilts occur while measuring. It is determined whether the subject has hamstring retraction if he scores less than 160º.	Baseline, 2 months and 3 months after intervention commencement

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Changes in maximum isometric hamstring strength	measured using a digital dynamometer. Participants are placed in a prone position on the stretcher with the lower limb chosen for measurement in a 90º knee flexion (position determined visually). The dynamometer is placed on the subject´s heel. Then, an increasing force towards the knee extension is applied for 3-5 seconds. Subjects must try to maintain this position without allowing the knee to extend. The measurement is taken when the subject begins to extend his knee. Three measurements are taken in the same position leaving 30 seconds of rest in between. Finally, the average of the three measurements is taken.	Baseline, 2 months and 3 months after intervention commencement

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Changes on tibial nerve pressure pain threshold	measured with a pressure algometer. Participants are placed in a prone position on the stretcher with both lower limbs extended. Measurements are taken in the popliteal fossa at the midpoint of the knee flexor line. The subject is instructed to report when pain and/or discomfort begins to be noticeable. Three different measurements are taken on the dominant leg leaving a 10 second rest in between. The pressure pain threshold value is the mean of the three measurements obtained.	Baseline, 2 months and 3 months after intervention commencement

Collaborators and Investigators

• Sponsor: University of Jaén
• Investigators: Principal Investigator: Juan Mínguez, University of Alcalá, Madrid, Spain

Study record dates

Study Major Dates

• Study Start (Actual): April 22, 2022
• Primary Completion (Actual): July 28, 2022
• Study Completion (Actual): July 28, 2022

Study Registration Dates

• First Submitted: April 15, 2022
• First Submitted That Met QC Criteria: April 21, 2022
• First Posted (Actual): April 25, 2022

Study Record Updates

• Last Update Posted (Actual): July 29, 2022
• Last Update Submitted That Met QC Criteria: July 28, 2022
• Last Verified: July 1, 2022

More Information

Terms related to this study

• Other Study ID Numbers: CEIM/HU/2019/36

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No