Evaluation of Corneal Endothelial Changes After Uneventful Phacoemulsification in Diabetic and Non-diabetic Patients in Relation to the Level of Glcosylated Hemoglobin Level

Evaluation of Corneal Endothelial Changes After Uneventful Phacoemulsification in Diabetic and Non-diabetic Patients in Relation to the Level of Glcosylated Hemoglobin Level

Sponsors

Lead Sponsor: Marwa Ahmed

Source Cairo University
Brief Summary

Evaluation of corneal endothelial changes after uneventful phacoemulsification in diabetic and non-diabetic patients using specular biomicroscopy in relation to the level of glcosylated hemoglobin level

Detailed Description

86 patients will be divided into two equal groups of diabetic and non-diabetic patients will undergo phacoemulsification of cataract will be evaluated thier endocelium before surgery and 3 weeks after surgery to detect the effect of level of glcosylated hemoglobin on the endothelial changes after uneventful phacoemulsification

Overall Status Recruiting
Start Date 2022-05-20
Completion Date 2022-11-17
Primary Completion Date 2022-11-17
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
Defferentiate patients into diabetic and non-diabetic patients according to the endothelial changes after uneventful phacoemulsification 6 monthes
Enrollment 68
Condition
Intervention

Intervention Type: Device

Intervention Name: Specular biomicroscopy

Description: Specular microscopy will be done before and 3 weeks after cataract surgery

Eligibility

Criteria:

Inclusion Criteria: - Diabetics and non-diabetic patients undergo cataract surgery - Age between 50-60 years old - Corrected distance visual acuity<0.4 - Gender: both genders. Exclusion Criteria: - Chronic Ocular diseases (glaucoma,uveitis, amblyopia, strabismus,keratoconus, corneal opacity). - corneal dystrophy History of previous keratitis or viral corneal infection. Corneal dystrophy Ocular trauma. Previous ocular surgery. Complicated cataract surgery

Gender:

All

Minimum Age:

50 Years

Maximum Age:

70 Years

Healthy Volunteers:

No

Overall Official
Last Name Role Affiliation
Mohamed A Hosny, MD Principal Investigator Cairo University
Overall Contact

Last Name: Marwa A Abdelaal

Phone: 01129875785

Email: [email protected]

Location
Facility: Status: Contact: Cairo University Mohamed A Hosny 01000007676 [email protected]
Location Countries

Egypt

Verification Date

2022-06-01

Responsible Party

Type: Sponsor-Investigator

Investigator Affiliation: Cairo University

Investigator Full Name: Marwa Ahmed

Investigator Title: Clinical professor

Has Expanded Access No
Number Of Arms 2
Arm Group

Label: Diabetic patient

Type: Active Comparator

Description: Patient with diabetes will undergo cataract surgery

Label: Non diabetic patients

Type: Active Comparator

Description: Healthy non diabetic patients will undergo cataract surgery

Study Design Info

Allocation: Non-Randomized

Intervention Model: Parallel Assignment

Primary Purpose: Prevention

Masking: Single (Participant)

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