Evaluation of Antioxidant and Anti-inflammatory Effect of Matcha Tea Intake on Periodontal Health

December 22, 2023 updated by: Hayder Raad Abdulbaqi

Aim of the study:

This study aims to evaluate the antioxidant and beneficial effects of matcha tea daily intake on periodontal health.

Objectives:

  • To evaluate the salivary level of antioxidants (catalase, total antioxidant capacity) after matcha tea intake compared to green tea over a period of one month.
  • To evaluate the clinical periodontal parameters including bleeding on probing (BOP), probing pocket depth (PPD) and plaque index (PI) after matcha tea intake compared to green tea over a period of one month.
  • To evaluate the salivary levels of IL-1B after matcha tea intake compared to green tea over a period of one month.

Study Overview

Status

Active, not recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

40

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Iraq
      • Baghdad, Iraq
        • Universality of Baghdad, College of dentistry

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 40 years (Adult)

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • • having at least 20 teeth,

    • underwent no medical treatment during the last 3 months before examination and sampling,
    • non-smoker,
    • no history of systemic disease,
    • gingivitis patient (having >10% bleeding sites with no PPD >3 mm).

Exclusion Criteria:

  • • wore orthodontic appliances,

    • pregnant or currently in the breast-feeding period,
    • periodontitis patient,
    • smoker,
    • has a history of systemic disease.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: green tea group
Mahmood Green Tea Sri Lanka. It will be given 2 cups / day for 30 days.
Dietary supplement: green tea
It will be given 2 cups / day for 30 days. To prepare each cup, a tea pack will be immersed into a cup of hot water.
Experimental: matcha tea group
Jade Leaf Organic Japanese Matcha, USA. It will be given 2 cups / day for 30 days.
Dietary supplement: matcha tea
It will be given 2 cups / day for 30 days. To prepare each cup, a tea pack will be immersed into a cup of hot water.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
change in salivary level of antioxidant marker
Time Frame: 30 Days (baseline to one moth of tea intake)
change in level of catalase enzyme in ku/L
30 Days (baseline to one moth of tea intake)
change in salivary level of ant-inflammatory marker
Time Frame: 30 Days (baseline to one moth of tea intake)
change in level of interleukin- one beta (IL-1B) in pg/L
30 Days (baseline to one moth of tea intake)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
change in percentage of bleeding on probing (BOP)
Time Frame: 30 Days (baseline to one moth of tea intake)
change in BOP percentage. less percentage means less inflammation in gingival tissue
30 Days (baseline to one moth of tea intake)
change in plaque index (PI) scores
Time Frame: 30 Days (baseline to one moth of tea intake)
change in PI scores. less scores mean less dental plaque accumulated onto teeth surfaces
30 Days (baseline to one moth of tea intake)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hayder Raad Abdulbaqi

Investigators

  • Study Director: HIND KAREEM, BDS, University of Baghdad

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 25, 2022

Primary Completion (Estimated)

December 30, 2023

Study Completion (Estimated)

July 12, 2024

Study Registration Dates

First Submitted

December 11, 2022

First Submitted That Met QC Criteria

January 11, 2023

First Posted (Actual)

January 12, 2023

Study Record Updates

Last Update Posted (Estimated)

December 27, 2023

Last Update Submitted That Met QC Criteria

December 22, 2023

Last Verified

December 1, 2023

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • matcha on periodontal health

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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