Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

The main goal of this study is to tests the effect of incentivizing achievement of self-identified, personal harm reduction goals (Contingency management or CM) compared with standard of care (peer harm reduction service with incentives for peer visits) to increase the reach and effectiveness of methamphetamine (MA) harm reduction services.

Study Overview

• Status: Recruiting
• Conditions: Methamphetamine Abuse
• Intervention / Treatment: Behavioral: Peer Contingency Management; Behavioral: Standard of Care Contingency Management

Detailed Description

Using a hybrid type 1 effectiveness-implementation framework and stepped-wedge design, this study will randomize eighteen community-based peer harm reduction sites to provide contingency management incentives for achieving self-identified harm reduction goals set with peer specialists using a participant-driven harm reduction goal-setting process (e.g. completing overdose prevention and supply training, daily life goals, treatment and care goals, relationship and social support goals) versus standard of care contingency management (i.e. incentives for peer encounter attendance).

• Study Type: Interventional
• Enrollment (Estimated): 1800
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Todd Korthuis, MD, MPH; Phone Number: 503494-8044; Email: korthuis@ohsu.edu
• Study Contact Backup: Name: Sara McCrimmon, MPH; Email: mccrimmo@ohsu.edu

Study Locations

• United States
  • Oregon
    • Portland, Oregon, United States, 97239
      • Recruiting
      • Oregon Health & Science University
      • Contact: Todd Korthuis; Email: korthuis@ohsu.edu
    • Portland, Oregon, United States, 97232
      • Recruiting
      • Comagine Health
      • Contact: Erin Stack; Email: estack@comagine.org

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 105 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

This intervention is at the site level. Community-based organization sites are eligible if they:

• Use peer support specialists to provide direct outreach and harm reduction services to people who use drugs
• Are willing to be trained in the two strategies for peer-facilitated contingency management

De-identified administrative data is used to identify an analytic sample of clients who:

• Reported past 30-day methamphetamine use at community-based organization intake.

Exclusion Criteria:

Community-based organization sites who:

• Do not use peer support specialists to provide direct outreach and harm reduction services to people who use drugs
• Are not willing to be trained in the two strategies for peer-facilitated contingency management

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Supportive Care
• Allocation: Randomized
• Interventional Model: Sequential Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: PEER-CM; Peer-facilitated contingency management (PEER-CM).	Behavioral: Peer Contingency Management; Participants allocated to peer-facilitated contingency management will receive incentives for achieving self-identified harm reduction goals set with peer specialists using a participant-driven harm reduction goal-setting process (e.g. completing overdose prevention and supply training, daily life goals, treatment and care goals, relationship and social support goals); Other Names: PEER-CM
Active Comparator: Standard of Care; Standard of care contingency management.	Behavioral: Standard of Care Contingency Management; Participants allocated to standard of care contingency management will receive incentives for peer encounters.; Other Names: Standard of Care

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Number of participants who overdose	Test the impact of incentives for achieving self-identified, personal harm reduction goals on the likelihood of overdose among people using methamphetamine at 6 months from enrollment identified through completed assessment.	6 months from baseline
Number of participants who achieve self-identified goals	Determine whether incentives for achieving self-identified, personal harm reduction goals increases engagement with harm reduction services at 6 months from enrollment identified through completed assessment.	6 months from baseline
Number of participants who engage in substance use disorder treatment	Determine whether incentives for achieving self-identified, personal harm reduction goals increases engagement with treatment services at 6 months from enrollment identified through completed assessment.	6 months from baseline

Collaborators and Investigators

• Sponsor: Oregon Health and Science University
• Collaborators: Oregon Health Authority; Comagine Health

Study record dates

Study Major Dates

• Study Start (Actual): November 13, 2023
• Primary Completion (Estimated): June 30, 2025
• Study Completion (Estimated): September 30, 2026

Study Registration Dates

• First Submitted: January 17, 2023
• First Submitted That Met QC Criteria: January 17, 2023
• First Posted (Actual): January 26, 2023

Study Record Updates

• Last Update Posted (Actual): March 26, 2024
• Last Update Submitted That Met QC Criteria: March 25, 2024
• Last Verified: March 1, 2024

More Information

Terms related to this study

• Other Study ID Numbers: PEER-CM

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No